Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18345594 | 0.98 | TAAR1 (0.62) | MAPTTAAR1RAD52KMT2ASIRT2 | |
| SCHEMBL1872944 | 0.87 | MAPT (0.64) | MAPTHSD17B10BAZ2BLMNACYP1A2 | |
| SCHEMBL18345852 | 0.87 | TAAR1 (0.59) | MAPTTAAR1RAD52KMT2ASIRT2 | |
| SCHEMBL12868071 | 0.85 | MAPT (0.60) | MAPTRAD52KMT2AHSD17B10BAZ2B | |
| SCHEMBL30228634 | 0.81 | TAAR1 (0.59) | TAAR1RAD52KMT2ASIRT2HSD17B10 | |
| SCHEMBL2313213 | 0.81 | TAAR1 (0.59) | TAAR1RAD52KMT2ASIRT2HSD17B10 | |
| SCHEMBL2243566 | 0.81 | PARP1 (0.67) | TAAR1RAD52KMT2ASIRT2HSD17B10 | |
| SCHEMBL2980510 | 0.81 | SIRT2 (0.72) | MAPTTAAR1RAD52KMT2ASIRT2 | |
| Hydrochloric Acid SCHEMBL21630948 | 0.79 | PARP1 (0.65) | TAAR1RAD52KMT2ASIRT2HSD17B10 | |
| Hydrochloric Acid SCHEMBL8508190 | 0.79 | TAAR1 (0.62) | TAAR1RAD52KMT2ASIRT2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4682146-A1 | COMPOSITION INCLUDING NOVEL PYRIDOINDOLE DERIVATIVE COMPOUND AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISEASES | Neurotarge Co., Ltd. (KR) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024191255-A1 | COMPOSITION INCLUDING NOVEL PYRIDOINDOLE DERIVATIVE COMPOUND AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISEASES | 한국과학기술연구원 | 2024-09-19 | — | — | WO | disclosed |
| EP-3820867-B1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CYSTIC FIBROSIS | FONDAZIONE ST ITALIANO TECNOLOGIA (IT) | 2023-09-13 | — | — | EP | disclosed |
| US-20210292324-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CYSTIC FIBROSIS | ISTITUTO GIANNINA GASLINI (IT) | 2021-09-23 | — | — | US | disclosed |
| EP-3313837-B1 | CARBOLINE ANTIPARASITICS | ZOETIS SERVICES LLC (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10570129-B2 | Carboline antiparasitics | ZOETIS SERVICES LLC (US) | 2020-02-25 | — | — | US | disclosed |
| US-20200031822-A1 | CARBOLINE ANTIPARASITICS | ZOETIS SERVICES LLC (US) | 2020-01-30 | — | — | US | disclosed |
| WO-2020012427-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CYSTIC FIBROSIS | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2020-01-16 | — | — | WO | disclosed |
| US-10183011-B2 | Anti-depression compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-01-22 | — | — | US | disclosed |
| US-20180318255-A1 | Pro-Neurogenic Compounds | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2018-11-08 | — | — | US | disclosed |
| EP-2170879-B1 | 1-CYANOCYCLOPROPYL-DERIVATIVES AS CATHEPSIN K INHIBITORS | ASTRAZENECA AB (SE) | 2013-01-16 | — | — | EP | disclosed |
| US-20120022096-A1 | PRO-NEUROGENIC COMPOUNDS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2012006419-A2 | PRO-NEUROGENIC COMPOUNDS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-01-12 | — | — | WO | disclosed |
| US-8008279-B2 | Compound—827 | ASTRAZENECA AB (SE) | 2011-08-30 | — | — | US | disclosed |
| US-7772245-B2 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-20090012077-A1 | Novel Compound - 827 | ASTRAZENECA AB (SE) | 2009-01-08 | — | — | US | disclosed |
| US-20060199829-A1 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS, INC. | 2006-09-07 | — | — | US | disclosed |
| EP-1414819-B1 | THERAPEUTIC 1H-PYRIDO[4,3-b]INDOLES | PHARMACIA & UPJOHN CO LLC (US) | 2005-10-12 | — | — | EP | disclosed |
| US-6849640-B2 | Therapeutic 1H-pyrido [4,3-b] indoles | PHARMACIA & UPJOHN COMPANY (US) | 2005-02-01 | — | — | US | disclosed |
| US-20030060464-A1 | Therapeutic 1H-pyrido [ 4, 3-b ] indoles | PHARMACIA & UPJOHN COMPANY | 2003-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022096-A1 | PRO-NEUROGENIC COMPOUNDS | BDNF, GAP43, DCX | MAPT 136/4885TAAR1 2341/4885RAD52 3297/4885 |
| US-20180318255-A1 | Pro-Neurogenic Compounds | BDNF, GAP43, DCX | MAPT 136/4885TAAR1 2341/4885RAD52 3297/4885 |
| US-20060199829-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC2, HDAC11 | MAPT 2758/4885TAAR1 4360/4885RAD52 563/4885 |
| US-10183011-B2 | Anti-depression compounds | BDNF, DCX, GAP43 | MAPT 142/4885TAAR1 3126/4885RAD52 2718/4885 |
| US-10570129-B2 | Carboline antiparasitics | ADRA1D, DRD1, CHRM1 | MAPT 4298/4885TAAR1 837/4885RAD52 2411/4885 |
| US-20210292324-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CYSTIC FIBROSIS | CFTR, ABCB11, ABCC5 | MAPT 4258/4885TAAR1 3882/4885RAD52 4798/4885 |
| US-20090012077-A1 | Novel Compound - 827 | CTSS, CTSF, CTSB | MAPT 2312/4885TAAR1 4785/4885RAD52 2930/4885 |
| US-20030060464-A1 | Therapeutic 1H-pyrido [ 4, 3-b ] indoles | HTR3B, HTR4, HTR3C | MAPT 1262/4885TAAR1 74/4885RAD52 3598/4885 |
| US-20200031822-A1 | CARBOLINE ANTIPARASITICS | DRD1, ADRA1D, DRD2 | MAPT 4336/4885TAAR1 507/4885RAD52 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.