Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412893 | 0.84 | KDM4E (0.32) | MAOAMAOBACLYFABP4CISD1 | |
| SCHEMBL412797 | 0.75 | ALDH1A1 (0.38) | KDM4CMAOAMAOBBCL2L1MCL1 | |
| SCHEMBL411957 | 0.70 | CAMKK2 (0.35) | KDM4CMAOAMAOBMAPTALDH1A1 | |
| SCHEMBL13715485 | 0.68 | KDM4E (0.58) | MEN1KMT2AKDM4EPLA2G1BMAPT | |
| SCHEMBL3343641 | 0.65 | NR3C1 (0.45) | MCL1ACLYMEN1KMT2AKDM4E | |
| SCHEMBL4032987 | 0.63 | LMNA (0.45) | ACLYMEN1KMT2APLA2G1BMAPT | |
| SCHEMBL7924637 | 0.63 | TSHR (0.47) | BCL2L1MCL1MEN1KMT2AKDM4E | |
| SCHEMBL108571 | 0.63 | TSHR (0.52) | MEN1KMT2APLA2G1BMAPTATG4B | |
| SCHEMBL3135874 | 0.62 | KDM4E (0.49) | KDM4CFABP4MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL9649707 | 0.62 | LMNA (0.44) | ACLYMEN1KMT2APLA2G1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021519-A1 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENTS AND FELLOWS OF HARVARD COLLEGE (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2010033906-A2 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-03-25 | — | — | WO | disclosed |