Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Etidronic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS known ✓ | P14324 | 4/20 | 0.38 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etidronic Acid SCHEMBL11334405 | 0.94 | LMNA (0.48) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL20292659 | 0.94 | LMNA (0.48) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL11329561 | 0.94 | LMNA (0.48) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL16321621 | 0.92 | LMNA (0.46) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL1649923 | 0.88 | LMNA (0.53) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL157065 | 0.85 | LMNA (0.47) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL5338103 | 0.83 | LMNA (0.63) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL1515049 | 0.83 | LMNA (0.63) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL5933440 | 0.82 | LMNA (0.53) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL29631751 | 0.81 | LMNA (0.60) | LMNAKDM4ECYP2C19KMT2AFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2830997-B1 | DISPERSED CALCIUM CARBONATE CONTAINING MATERIAL FOR AN IMPROVED STABILITY UNDER ALKALINE CONDITIONS | OMYA INT AG (CH) | 2018-06-27 | — | — | EP | claimed |
| EP-4615947-A1 | FATTY ACID SOAP BARS COMPRISING POTASSIUM SOAP | Unilever IP Holdings B.V. (NL) | 2025-09-17 | — | — | EP | disclosed |
| EP-2907894-B2 | Method for production of a substrate with a chromium VI free and cobalt-free passivation | DOERKEN EWALD AG (DE) | 2025-03-19 | — | — | EP | disclosed |
| EP-3931294-B1 | BAR COMPOSITIONS COMPRISING C10 SOAP WHILE MINIMIZING RATIO OF UNSATURATED C18 SOAP TO CAPRATE | UNILEVER IP HOLDINGS B V (NL) | 2024-08-21 | — | — | EP | disclosed |
| US-12006494-B2 | Bar compositions comprising C10 soap while minimizing ratio of unsaturated C18 soap to caprate | CONOPCO, INC. (US) | 2024-06-11 | — | — | US | disclosed |
| WO-2024099785-A1 | FATTY ACID SOAP BARS COMPRISING POTASSIUM SOAP | UNILEVER IP HOLDINGS B.V. (NL) | 2024-05-16 | — | — | WO | disclosed |
| US-20220135910-A1 | BAR COMPOSITIONS COMPRISING C10 SOAP WHILE MINIMIZING RATIO OF UNSATURATED C18 SOAP TO CAPRATE | CONOPCO, INC., D/B/A UNILEVER (US) | 2022-05-05 | — | — | US | disclosed |
| EP-2759621-B1 | Reactive-type chemical conversion treatment composition and production method of member with chemical conversion coated surface | YUKEN IND CO LTD (JP) | 2021-06-02 | — | — | EP | disclosed |
| US-9915006-B2 | Reactive-type chemical conversion treatment composition and production method of member with chemical conversion coated surface | YUKEN INDUSTRY CO., LTD. (JP) | 2018-03-13 | — | — | US | disclosed |
| US-20170009363-A1 | REACTIVE-TYPE CHEMICAL CONVERSION TREATMENT COMPOSITION AND PRODUCTION METHOD OF MEMBER WITH CHEMICAL CONVERSION COATED SURFACE | YUKEN INDUSTRY CO., LTD. (JP) | 2017-01-12 | — | — | US | disclosed |
| EP-0154474-A2 | Bis(aminoalkyl)piperazine derivatives and their use as metal ion control agents and cement set retarding agents | THE DOW CHEMICAL COMPANY (US) | 1985-09-11 | — | — | EP | disclosed |
| WO-1985003698-A1 | BIS(AMINOALKYL)PIPERAZINE DERIVATIVES AND THEIR USE AS METAL ION CONTROL AGENTS AND CEMENT SET RETARDING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1985-08-29 | — | — | WO | disclosed |
| EP-0136790-A2 | New additives for retarding setting of cement from methylenephosphonated aminohydrocarbylpiperazine-urea adducts | THE DOW CHEMICAL COMPANY (US) | 1985-04-10 | — | — | EP | disclosed |
| WO-1985001043-A1 | USE OF METHYLENE PHOSPHONIC ACID COMPOSITIONS DERIVED FROM AMINOHYDROCARBYLPIPERAZINEUREA ADDUCTS AS CEMENT RETARDERS | THE DOW CHEMICAL COMPANY (US) | 1985-03-14 | — | — | WO | disclosed |
| US-4500356-A | EXTENDS THICKENING TIME | THE DOW CHEMICAL COMPANY (US) | 1985-02-19 | — | — | US | disclosed |
| US-4472200-A | New additives for retarding setting of cement from methylenephosphonated aminohydrocarbylpiperazine-urea adducts | THE DOW CHEMICAL COMPANY (US) | 1984-09-18 | — | — | US | disclosed |
| US-4468252-A | Set retarding additives for cement from aminomethylenephosphonic acid derivatives | THE DOW CHEMICAL COMPANY (US) | 1984-08-28 | — | — | US | disclosed |
| US-4466835-A | DICYCLOPENTADIENE PHOSPHONATE COMPOUNDS | THE DOW CHEMICAL COMPANY (US) | 1984-08-21 | — | — | US | disclosed |
| US-4466836-A | PHOSPHONATE COMPOUNDS CONTAINING PYRAZINE RINGS | THE DOW CHEMICAL COMPANY (US) | 1984-08-21 | — | — | US | disclosed |
| US-4169086-A | SALT OF ACYL ESTER OF HYDROXYMETHANEPHOSPHONIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |