Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Etidronic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS known ✓ | P14324 | 8/20 | 0.43 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.43 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etidronic Acid SCHEMBL1649923 | 0.88 | LMNA (0.53) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL10957062 | 0.86 | LMNA (0.77) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL4136699 | 0.83 | LMNA (0.48) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL1515049 | 0.83 | LMNA (0.63) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL5933440 | 0.82 | LMNA (0.53) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL10957072 | 0.81 | LMNA (0.60) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL29631751 | 0.81 | LMNA (0.60) | LMNAKDM4ECYP2C19KMT2AFDPS | |
| Etidronic Acid SCHEMBL10532992 | 0.78 | LMNA (1.00) | LMNAFDPSGGPS1PGK1PGK2 | |
| Etidronic Acid SCHEMBL18607 | 0.78 | LMNA (1.00) | LMNAFDPSGGPS1PGK1PGK2 | |
| Etidronic Acid SCHEMBL17580249 | 0.78 | LMNA (0.63) | LMNAKDM4ECYP2C19KMT2AFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1760142-B2 | Laundry Scent Customization | PROCTER & GAMBLE (US) | 2020-07-15 | — | — | EP | disclosed |
| EP-1760142-B1 | Laundry Scent Customization | PROCTER & GAMBLE (US) | 2013-09-18 | — | — | EP | disclosed |
| WO-2007026331-A1 | LAUNDRY SCENT CUSTOMIZATION | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |
| US-20070054815-A1 | Laundry scent customization | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | US | disclosed |
| EP-1760142-A1 | Laundry Scent Customization | The Procter and Gamble Company (US) | 2007-03-07 | — | — | EP | disclosed |