Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL31514902 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10 | |
| Water SCHEMBL4432268 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10 | |
| Water SCHEMBL31298571 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRHSD17B10 | |
| Potassium SCHEMBL29449366 | 0.97 | ALDH1A1 (0.35) | ALDH1A1LMNATSHRHSD17B10 | |
| Potassium SCHEMBL243586 | 0.97 | ALDH1A1 (0.35) | ALDH1A1LMNATSHRHSD17B10 | |
| Potassium SCHEMBL3422897 | 0.97 | ALDH1A1 (0.35) | ALDH1A1LMNATSHRHSD17B10 | |
| Potassium SCHEMBL245761 | 0.97 | ALDH1A1 (0.35) | ALDH1A1LMNATSHRHSD17B10 | |
| Water SCHEMBL6065928 | 0.97 | ALDH1A1 (0.35) | ALDH1A1LMNATSHRHSD17B10 | |
| Water SCHEMBL3409395 | 0.97 | ALDH1A1 (0.35) | ALDH1A1LMNATSHRHSD17B10 | |
| Water SCHEMBL29283164 | 0.97 | ALDH1A1 (0.35) | ALDH1A1LMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116359516-A | Kit for detecting total IgE content of serum and application | 郑州安图生物工程股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-119920630-A | Porous carbon material, preparation method thereof, lithium ion capacitor positive electrode and lithium ion capacitor | 中国石油化工股份有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-114740120-B | Method for simultaneously and quantitatively determining abiraterone and five metabolites thereof and application | 武汉宏韧生物医药股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117368379-A | Method for high-flux detection of catecholamines and metabolites thereof by liquid chromatography electrochemical method | 北京豪思生物科技股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-116359516-A | Kit for detecting total IgE content of serum and application | 郑州安图生物工程股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| US-8916614-B2 | Lindane lotion and methods | WOCKHARDT EU OPERATIONS (SWISS) AG (CH) | 2014-12-23 | — | — | US | disclosed |
| US-20090105276-A1 | LINDANE LOTION AND METHODS | WOCKHARDT EU OPERATIONS (SWISS) AG (CH) | 2009-04-23 | — | — | US | disclosed |
| EP-0316834-B1 | STEROID CREAM FORMULATION | E.R. Squibb & Sons, Inc. (US) | 1992-06-24 | — | — | EP | disclosed |
| US-4883792-A | ANTIFUNGAL CREAM CONTAINING TIPREDANE | E.R. SQUIBB & SONS, INC., A DE CORP. | 1989-11-28 | — | — | US | disclosed |
| US-4868170-A | ANTIINFLAMMATORY, OXIDATION RESISTANCE | E. R. SQUIBB & SONS, INC. (US) | 1989-09-19 | — | — | US | disclosed |
| US-4868169-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0316834-A1 | Steroid cream formulation | E.R. Squibb & Sons, Inc. (US) | 1989-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105276-A1 | LINDANE LOTION AND METHODS | LAGE3, LOXL3, LOXL1 | ALDH1A1 272/4885LMNA 904/4885TSHR 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.