Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 5/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31722598 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL111536 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL31277237 | 0.78 | CA2 (0.54) | ALDH1A1CYP3A4TSHRAPPPOLB | |
| SCHEMBL470124 | 0.78 | CA2 (0.54) | ALDH1A1CYP3A4TSHRAPPPOLB | |
| SCHEMBL31441812 | 0.78 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL29375147 | 0.76 | ALDH1A1 (0.67) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL197234 | 0.76 | APP (0.38) | CYP3A4TSHRAPPIDO1MAPT | |
| SCHEMBL29399235 | 0.76 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL48945 | 0.76 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL64099 | 0.76 | ALDH1A1 (0.67) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431230-A | Compounds for inhibiting alpha 4 beta 7 integrin | 吉利德科学公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-114222730-B | Compounds for inhibiting alpha 4 beta 7 integrin | 吉利德科学公司 | 2024-09-10 | — | — | CN | disclosed |
| US-11603350-B2 | Compound, composition, cured object, optically anisotropic body, and reflective film | FUJIFILM CORPORATION (JP) | 2023-03-14 | — | — | US | disclosed |
| US-11578069-B2 | Compounds for inhibition of α4 β7 integrin | GILEAD SCIENCES, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| US-11578069-B2 | Compounds for inhibition of α4 β7 integrin | GILEAD SCIENCES, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| EP-4013499-A1 | COMPOUNDS FOR INHIBITION OF ALPHA 4 BETA 7 INTEGRIN | GILEAD SCIENCES, INC. (US) | 2022-06-22 | — | — | EP | disclosed |
| CN-114222730-A | Compounds for inhibiting alpha 4 beta 7 integrins | 吉利德科学公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-108025189-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2021-07-02 | — | — | CN | disclosed |
| US-20210053967-A1 | COMPOUNDS FOR INHIBITION OF ALPHA 4 BETA 7 INTEGRIN | GILEAD SCIENCES, INC. | 2021-02-25 | — | — | US | disclosed |
| US-20210053967-A1 | COMPOUNDS FOR INHIBITION OF ALPHA 4 BETA 7 INTEGRIN | GILEAD SCIENCES, INC. | 2021-02-25 | — | — | US | disclosed |
| WO-2014058747-A1 | 5-PHENOXY-3H-PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS HIV REVERSE TRANSCRIPTASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-04-17 | — | — | WO | disclosed |
| EP-1797050-B1 | HIV INHIBITING 1.2.4-TRIAZIN-6-ONE DERIVATES | JANSSEN PHARMACEUTICA NV (BE) | 2013-10-23 | — | — | EP | disclosed |
| US-20120142672-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| CN-102482276-A | Heterocyclic compounds and their use | TAKEDA PHARMACEUTICAL | 2012-05-30 | — | — | CN | disclosed |
| EP-2455380-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-05-23 | — | — | EP | disclosed |
| WO-2012061299-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| US-20110160196-A1 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. | 2011-06-30 | — | — | US | disclosed |
| CN-102036972-A | Treatment of duchenne muscular dystrophy | SUMMIT CORP PLC | 2011-04-27 | — | — | CN | disclosed |
| US-7923554-B2 | HIV inhibiting 1,2,4-triazin-6-one derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2011-04-12 | — | — | US | disclosed |
| US-20090012092-A1 | Hiv Inhibiting 1,2,4-Triazin-6-One Derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012092-A1 | Hiv Inhibiting 1,2,4-Triazin-6-One Derivatives | NCOR1, NR1H3, NCOA3 | ALDH1A1 3489/4885CYP3A4 143/4885TDP1 4113/4885 |
| US-20110160196-A1 | FACTOR XA INHIBITORS | TFPI, F12, F11 | ALDH1A1 1468/4885CYP3A4 277/4885TDP1 1486/4885 |
| US-11578069-B2 | Compounds for inhibition of α4 β7 integrin | ITGB7, ITGB4, ITGA4 | ALDH1A1 830/4885CYP3A4 1987/4885TDP1 4649/4885 |
| US-20120142672-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | BACE1, APP, BACE2 | ALDH1A1 873/4885CYP3A4 908/4885TDP1 1955/4885 |
| US-11603350-B2 | Compound, composition, cured object, optically anisotropic body, and reflective film | FLNA, CFL1, MKI67 | ALDH1A1 886/4885CYP3A4 4346/4885TDP1 3813/4885 |
| US-20210053967-A1 | COMPOUNDS FOR INHIBITION OF ALPHA 4 BETA 7 INTEGRIN | ITGB7, ITGB4, ITGA4 | ALDH1A1 796/4885CYP3A4 2057/4885TDP1 4478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.