Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | FNTA | P49354 | 2/20 | 0.52 |
| ▸ | FNTB | P49356 | 2/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14846677 | 0.86 | FNTA (0.52) | KMT2ANPSR1MEN1FNTAFNTB | |
| SCHEMBL28966345 | 0.86 | FNTA (0.52) | KMT2ANPSR1MEN1FNTAFNTB | |
| SCHEMBL20353635 | 0.84 | FAAH (0.60) | KMT2ANPSR1MEN1FAAH | |
| SCHEMBL1704512 | 0.84 | ALDH1A1 (0.66) | KMT2ANPSR1MEN1FNTAFNTB | |
| SCHEMBL4192541 | 0.84 | KMT2A (0.56) | KMT2ANPSR1MEN1FNTAFNTB | |
| SCHEMBL24200046 | 0.83 | NPSR1 (0.58) | KMT2ANPSR1MEN1FNTAFNTB | |
| SCHEMBL29132085 | 0.82 | SIGMAR1 (0.59) | KMT2ANPSR1MEN1FNTAFNTB | |
| SCHEMBL4595454 | 0.82 | KMT2A (0.57) | KMT2ANPSR1MEN1FNTAFNTB | |
| SCHEMBL24199876 | 0.81 | SIGMAR1 (0.68) | ALDH1A1LMNAFAAHKDM4ETSHR | |
| SCHEMBL4175784 | 0.81 | PDK1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130317041-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-11-28 | — | — | US | disclosed |
| US-8536182-B2 | Benzylpiperazine derivatives and their medical use | GLAXO GROUP LIMITED (GB) | 2013-09-17 | — | — | US | disclosed |
| US-20090054456-A1 | BENZYLPIPERAZINE DERIVATIVES AND THEIR MEDICAL USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054456-A1 | BENZYLPIPERAZINE DERIVATIVES AND THEIR MEDICAL USE | GPR68, GPR88, GPR55 | KMT2A 3278/4885NPSR1 133/4885MEN1 3996/4885 |
| US-20130317041-A1 | COMPOUNDS | GPR68, GPR88, GPR35 | KMT2A 3208/4885NPSR1 136/4885MEN1 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.