Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4195751 | 0.84 | MEN1 (0.53) | MEN1KMT2APOLBALOX15CYP1A2 | |
| SCHEMBL4198230 | 0.84 | ALOX15 (0.63) | MEN1KMT2APOLBALOX15CYP1A2 | |
| SCHEMBL4186735 | 0.82 | ALOX15 (0.65) | KMT2AALOX15CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4205361 | 0.82 | RAB9A (0.56) | MEN1KMT2APOLBALOX15CYP1A2 | |
| SCHEMBL23246073 | 0.79 | GRM4 (0.57) | MEN1KMT2APOLBALOX15MAPT | |
| SCHEMBL4198299 | 0.77 | KCNMA1 (0.59) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL4199011 | 0.76 | NPC1 (0.53) | MEN1KMT2APOLBALOX15CYP1A2 | |
| SCHEMBL6004222 | 0.75 | TYK2 (0.53) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL6003795 | 0.74 | RAB9A (0.58) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL4187732 | 0.74 | KMT2A (0.54) | MEN1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088463-A1 | Pyrazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088463-A1 | Pyrazoles Useful in the Treatment of Inflammation | ALOX15, ALOX5, ALOX15B | MEN1 4164/4885KMT2A 4552/4885POLB 2613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.