Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.52 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205361 | 0.87 | RAB9A (0.56) | KMT2ATAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL4199011 | 0.87 | NPC1 (0.53) | KMT2AMEN1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL169574 | 0.86 | ALOX15 (0.47) | SMN1; SMN2ALDH1A1HTTRAB9AMAPT | |
| SCHEMBL18027798 | 0.78 | RAB9A (0.54) | SMN1; SMN2ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL30677473 | 0.77 | MEN1 (0.58) | KMT2AMEN1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9817347 | 0.75 | GAA (0.74) | KMT2ATAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL4198230 | 0.75 | ALOX15 (0.63) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL4449040 | 0.74 | TAS1R3 (0.69) | KMT2ATAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL4188965 | 0.74 | MEN1 (0.45) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL4202584 | 0.73 | RAB9A (0.51) | KMT2ATAS1R3TAS1R1TAS1R2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088463-A1 | Pyrazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-04-02 | — | — | US | disclosed |
| EP-1943225-A1 | PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007052000-A1 | PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088463-A1 | Pyrazoles Useful in the Treatment of Inflammation | ALOX15, ALOX5, ALOX15B | KMT2A 4552/4885TAS1R3 1932/4885TAS1R1 1661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.