Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30537232 | 1.00 | AR (0.50) | ARHTTHIF1AKDM4EALDH1A1 | |
| SCHEMBL27841783 | 0.95 | AR (0.46) | ARHTTHIF1AKDM4EALDH1A1 | |
| SCHEMBL2836254 | 0.93 | AR (0.43) | ARHTTHIF1AKDM4EALDH1A1 | |
| SCHEMBL17110992 | 0.90 | AR (0.46) | ARHTTHIF1AKDM4EALDH1A1 | |
| SCHEMBL14173282 | 0.87 | ACACB (0.47) | HTTTDP1SMN1; SMN2POLBLMNA | |
| SCHEMBL14173290 | 0.87 | ACACB (0.47) | HTTTDP1SMN1; SMN2POLBLMNA | |
| SCHEMBL13683377 | 0.87 | AR (0.39) | ARHTTHIF1AKDM4EALDH1A1 | |
| SCHEMBL4191438 | 0.85 | L3MBTL1 (0.41) | HTTALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL12055942 | 0.85 | HTT (0.47) | ARHTTHIF1AKDM4EALDH1A1 | |
| SCHEMBL27820400 | 0.85 | KDM4E (0.48) | ARHTTKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260132235-A1 | 2-Component Dental Materials Based On Crosslinked Polymeric Particles Bearing Acylthiourea Groups | IVOCLAR VIVADENT AG (LI) | 2026-05-14 | — | — | US | claimed |
| US-12514791-B2 | Aesthetic dental filling material having high curing depth | IVOCLAR VIVADENT AG (LI) | 2026-01-06 | — | — | US | claimed |
| US-20250352435-A1 | AESTHETIC DENTAL FILLING MATERIAL HAVING HIGH CURING DEPTH | IVOCLAR VIVADENT AG (LI) | 2025-11-20 | — | — | US | claimed |
| EP-4591847-A1 | 2-COMPONENT DENTAL MATERIALS BASED ON CROSSLINKED POLYMERIC PARTICLES BEARING ACYLTHIOUREA GROUPS | Ivoclar Vivadent AG (LI) | 2025-07-30 | — | — | EP | claimed |
| CN-114848503-B | Dental materials based on polymerizable thiourea derivatives | 义获嘉伟瓦登特公司 | 2025-02-25 | — | — | CN | claimed |
| US-20250017827-A1 | Acid-Stable Glass Fillers And Self-Adhesive Dental Composite Cements With Good Transparency Containing Them | IVOCLAR VIVADENT AG (LI) | 2025-01-16 | — | — | US | claimed |
| EP-4488243-A1 | ACID-STABLE GLASS FILLERS AND SELF-ADHESIVE DENTAL COMPOSITE CEMENTS CONTAINING SAME HAVING GOOD TRANSPARENCY | Ivoclar Vivadent AG (LI) | 2025-01-08 | — | — | EP | claimed |
| US-12083194-B2 | Dental materials based on polymerizable thiourea derivatives | IVOCLAR VIVADENT AG (LI) | 2024-09-10 | — | — | US | claimed |
| EP-4414390-A1 | ACYLTHIOUREA OLIGOMERS SUITABLE AS REDOX INITIATOR COMPONENTS AND RADICALLY POLYMERIZABLE COMPOSITIONS COMPRISING THEM | Ivoclar Vivadent AG (LI) | 2024-08-14 | — | — | EP | claimed |
| US-12043683-B2 | Dental materials based on redox systems with oligomeric cumene hydroperoxide derivatives | IVOCLAR VIVADENT AG (LI) | 2024-07-23 | — | — | US | claimed |
| US-20200165363-A1 | PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS | IVOCLAR VIVADENT AG (LI) | 2020-05-28 | — | — | US | claimed |
| US-20200054423-A1 | Monochromatic Dental Shaped Article And Blank For Making Dental Restorations | IVOCLAR VIVADENT AG (LI) | 2020-02-20 | — | — | US | claimed |
| EP-2987480-B1 | Photocurable dental composites with increasing opacity | IVOCLAR VIVADENT AG (LI) | 2019-06-19 | — | — | EP | claimed |
| EP-3278786-B1 | DENTAL MATERIALS ON THE BASIS OF VINYLCYCLOPROPANE DERIVATIVES CONTAINING URETHANE GROUPS | IVOCLAR VIVADENT AG (LI) | 2019-01-23 | — | — | EP | claimed |
| WO-2018167213-A1 | MONOCHROMATIC DENTAL SHAPED ARTICLE AND BLANK FOR MAKING DENTAL RESTORATIONS | IVOCLAR VIVADENT AG (LI) | 2018-09-20 | — | — | WO | claimed |
| EP-3375429-A1 | MONOCHROMATIC DENTAL MOLDED ARTICLE AND BLANK FOR THE PRODUCTION OF DENTAL RESTORATIONS | Ivoclar Vivadent AG (LI) | 2018-09-19 | — | — | EP | claimed |
| WO-2016026915-A1 | LIGHT-CURING DENTAL COMPOSITE WITH INCREASING OPACITY | IVOCLAR VIVADENT AG (LI) | 2016-02-25 | — | — | WO | claimed |
| EP-2987480-A1 | Photocurable dental composites with increasing opacity | Ivoclar Vivadent AG (LI) | 2016-02-24 | — | — | EP | claimed |
| US-20040122123-A1 | Pultrusion apparatus for continuous fabrication of fiber-reinforced plastic articles having a non-linear shape, methods of fabricating such articles, and compositions used therein | KUSY ROBERT P | 2004-06-24 | — | — | US | claimed |
| US-20020180112-A1 | Pultrusion apparatus for continuous fabrication of fiber-reinforced plastic articles having a non-linear shape, methods of fabricating such articles and compositions used therein | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2002-12-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132235-A1 | 2-Component Dental Materials Based On Crosslinked Polymeric Particles Bearing Acylthiourea Groups | HBG1, TCP1, GSTM1 | AR 3074/4885HTT 802/4885HIF1A 241/4885 |
| US-20200165363-A1 | PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS | MMAB, ALAD, SULT1E1 | AR 3613/4885HTT 439/4885HIF1A 739/4885 |
| US-12083194-B2 | Dental materials based on polymerizable thiourea derivatives | TAS2R10, PAM, HBG1 | AR 2689/4885HTT 574/4885HIF1A 586/4885 |
| US-12043683-B2 | Dental materials based on redox systems with oligomeric cumene hydroperoxide derivatives | CBR3, NR1H3, NR1I3 | AR 863/4885HTT 2557/4885HIF1A 1776/4885 |
| US-20250017827-A1 | Acid-Stable Glass Fillers And Self-Adhesive Dental Composite Cements With Good Transparency Containing Them | HAO2, HAO1, CDH1 | AR 2342/4885HTT 2078/4885HIF1A 1618/4885 |
| US-20250352435-A1 | AESTHETIC DENTAL FILLING MATERIAL HAVING HIGH CURING DEPTH | CAD, REV1, RAD51 | AR 1377/4885HTT 565/4885HIF1A 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.