Sugi Predict

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SCHEMBL4201371

SCHEMBL4201371

COc1ccc(C(NCc2ccc(O)c(OC)c2)c2ccc(OC)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.54
▸ CALM1 P0DP23 2/20 0.51
▸ GAA P10253 3/20 0.50
▸ FOS P01100 1/20 0.50
▸ TTR P02766 1/20 0.50
▸ JUN P05412 1/20 0.50
▸ ATM Q13315 1/20 0.50
▸ NR3C1 P04150 1/20 0.50
▸ HSD17B1 P14061 1/20 0.50
▸ HSD17B2 P37059 1/20 0.50
▸ BCHE P06276 1/20 0.49
▸ TYR P14679 1/20 0.49
▸ ACHE P22303 1/20 0.49
▸ PTPN1 P18031 1/20 0.48
▸ NOS2 P35228 1/20 0.48
▸ MMP1 P03956 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ TAAR1 Q96RJ0 2/20 0.48
▸ TSHR P16473 1/20 0.48
▸ MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4201306 0.87 GAA (0.61) TDP1GAAFOSTTRJUN
SCHEMBL11861031 0.79 FOS (0.63) TDP1GAAFOSTTRJUN
SCHEMBL5155165 0.76 TSHR (0.47) TDP1CALM1GAABCHETYR
SCHEMBL29212726 0.76 ALDH1A1 (0.71) GAAALDH1A1MAPT
SCHEMBL11969383 0.75 TAAR1 (0.62) TDP1CALM1GAAFOSTTR
SCHEMBL5833247 0.75 TAAR1 (0.62) TDP1CALM1GAAFOSTTR
SCHEMBL4210480 0.74 KMT2A (0.60) TDP1GAAATMTSHRKDM4E
SCHEMBL4612057 0.74 TAAR1 (0.61) TDP1CALM1GAAFOSTTR
SCHEMBL7739503 0.74 TAAR1 (0.61) TDP1CALM1GAAFOSTTR
SCHEMBL31512891 0.73 CALM1 (0.59) TDP1CALM1GAAFOSTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 — — US claimed
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same SYMRISE AG (DE) 2025-02-27 — — US claimed
EP-4469439-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-12-04 — — EP claimed
CN-118984825-A Novel cooling agent and preparation containing same 西姆莱斯股份公司 2024-11-19 — — CN claimed
EP-4452941-A1 ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-10-30 — — EP claimed
US-20240058259-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS FIRMENICH SA (CH) 2024-02-22 — — US claimed
US-20240000746-A1 New Cooling Agents and Preparations Containing Them SYMRISE AG (DE) 2024-01-04 — — US claimed
EP-4247791-A2 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2023-09-27 — — EP claimed
CN-116685575-A Novel cooling substances and formulations containing these cooling substances 西姆莱斯股份公司 2023-09-01 — — CN claimed
WO-2023143741-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 — — WO claimed
US-20210100245-A1 SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS BEDOUKIAN RESEARCH, INC. (US) 2021-04-08 — — US claimed
US-20210100242-A1 FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS BEDOUKIAN RESEARCH, INC. (US) 2021-04-08 — — US claimed
US-20200188289-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS FIRMENICH SA (CH) 2020-06-18 — — US claimed
EP-3624757-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS Firmenich SA (CH) 2020-03-25 — — EP claimed
CN-110621287-A Composition comprising essential oils 弗门尼舍有限公司 2019-12-27 — — CN claimed
US-10392371-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2019-08-27 — — US claimed
WO-2018211420-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS FIRMENICH SA (CH) 2018-11-22 — — WO claimed
US-20090035364-A1 PARA-SUBSTITUTED 2-ALKOXYPHENOL COMPOUNDS GIVAUDAN SA (CH) 2009-02-05 — — US claimed
EP-1996535-A2 PARA-SUBSTITUTED 2-ALKOXYPHENOL COMPOUNDS Givaudan SA (CH) 2008-12-03 — — EP claimed
WO-2007104175-A2 PARA-SUBSTITUTED 2-ALKOXYPHENOL COMPOUNDS GIVAUDAN SA (CH) 2007-09-20 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210100242-A1 FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS ACHE, NISCH, DDT TDP1 3879/4885CALM1 2324/4885GAA 2426/4885
US-20210100245-A1 SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS NOTUM, SGMS1, COASY TDP1 4760/4885CALM1 3363/4885GAA 3697/4885
US-10392371-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM4, TRPM6 TDP1 3125/4885CALM1 842/4885GAA 3828/4885
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same TAS2R5, TAS2R7, TAS2R8 TDP1 3866/4885CALM1 2689/4885GAA 88/4885
US-20240000746-A1 New Cooling Agents and Preparations Containing Them TTPA, TREH, TAS2R45 TDP1 1359/4885CALM1 2218/4885GAA 2325/4885
US-20250163006-A1 New Coolants, and Preparations Containing Same TTR, TAS2R5, TAS2R50 TDP1 1687/4885CALM1 1256/4885GAA 925/4885
US-20090035364-A1 PARA-SUBSTITUTED 2-ALKOXYPHENOL COMPOUNDS EBP, CYP1A1, CYP2E1 TDP1 1150/4885CALM1 3645/4885GAA 4473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.