Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.41 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.41 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.36 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL6943683 | 0.96 | ALDH1A1 (0.67) | ALDH1A1MAPTGAATSHRSMN1; SMN2 | |
| SCHEMBL147847 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MAPTGAATSHRSMN1; SMN2 | |
| SCHEMBL4552496 | 0.81 | MAPT (0.49) | ALDH1A1MAPTGAATSHRSMN1; SMN2 | |
| SCHEMBL1227388 | 0.80 | MAPT (1.00) | ALDH1A1MAPTGAATSHRSMN1; SMN2 | |
| SCHEMBL12506468 | 0.80 | MAPT (0.75) | ALDH1A1MAPTGAATSHRSMN1; SMN2 | |
| SCHEMBL9175776 | 0.78 | MAPT (0.72) | ALDH1A1MAPTGAATSHRSMN1; SMN2 | |
| SCHEMBL29414291 | 0.78 | GAA (0.95) | ALDH1A1MAPTGAATSHRSMN1; SMN2 | |
| SCHEMBL10433697 | 0.78 | GAA (0.95) | ALDH1A1MAPTGAATSHRSMN1; SMN2 | |
| SCHEMBL4213821 | 0.78 | ALDH1A1 (0.72) | ALDH1A1MAPTGAATSHRSMN1; SMN2 | |
| SCHEMBL15240 | 0.78 | ALDH1A1 (0.72) | ALDH1A1MAPTGAATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115287715-A | Production process of double-optical copper foil for medium-tensile-strength lithium battery | 广东盈华电子科技有限公司 | 2022-11-04 | — | — | CN | claimed |
| CN-115287715-A | Production process of double-optical copper foil for medium-tensile-strength lithium battery | 广东盈华电子科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| US-9664679-B2 | Lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160274105-A1 | Lateral Flow and Flow-through Bioassay Devices Based on Patterned Porous Media, Methods of Making Same, and Methods of Using Same | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2016-09-22 | — | — | US | disclosed |
| US-9193988-B2 | Lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-11-24 | — | — | US | disclosed |
| EP-2076775-B1 | LATERAL FLOW AND FLOW-THROUGH BIOASSAY BASED ON PATTERNED POROUS MEDIA, METHODS OF MAKING SAME, AND METHODS OF USING SAME | HARVARD COLLEGE (US) | 2015-08-19 | — | — | EP | disclosed |
| US-20140234881-A1 | LATERAL FLOW AND FLOW-THROUGH BIOASSAY DEVICES BASED ON PATTERNED POROUS MEDIA, METHODS OF MAKING SAME, AND METHODS OF USING SAME | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-08-21 | — | — | US | disclosed |
| US-8603832-B2 | Lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-12-10 | — | — | US | disclosed |
| US-20130128036-A1 | Lateral Flow and Flow-through Bioassay Devices Based on Patterned Porous Media, Methods of Making Same, and Methods of Using Same | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-05-23 | — | — | US | disclosed |
| US-8377710-B2 | Lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-02-19 | — | — | US | disclosed |
| US-20090298191-A1 | Lateral Flow and Flow-through Bioassay Devices Based On Patterned Porous Media, Methods of Making Same, and Methods of Using Same | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-12-03 | — | — | US | disclosed |
| EP-2076775-A2 | LATERAL FLOW AND FLOW-THROUGH BIOASSAY BASED ON PATTERNED POROUS MEDIA, METHODS OF MAKING SAME, AND METHODS OF USING SAME | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008049083-A2 | LATERAL FLOW AND FLOW-THROUGH BIOASSAY BASED ON PATTERNED POROUS MEDIA, METHODS OF MAKING SAME, AND METHODS OF USING SAME | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-04-24 | — | — | WO | disclosed |
| EP-0457214-A2 | Method and reagent composition for the determination of alanine aminotransferase and HBsAg antigen in the same biological specimen | SCLAVO S.p.A. (IT) | 1991-11-21 | — | — | EP | disclosed |