Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.36 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.33 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 13/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38664990 | 0.83 | MYC (0.65) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL275601 | 0.83 | MYC (0.65) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL3412051 | 0.83 | MYC (0.65) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL4217684 | 0.81 | ALDH1A1 (0.67) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| Methyl Red SCHEMBL29367969 | 0.80 | MYC (0.74) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| Methyl Red SCHEMBL4639900 | 0.80 | MYC (0.74) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| Methyl Red SCHEMBL38665474 | 0.80 | MYC (0.74) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| SCHEMBL8722208 | 0.78 | MAPT (0.48) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| Methyl Red SCHEMBL36580593 | 0.77 | MYC (0.74) | MAPTSMN1; SMN2ALDH1A1GAATP53 | |
| Zinc Ion SCHEMBL6943683 | 0.77 | ALDH1A1 (0.67) | MAPTSMN1; SMN2ALDH1A1GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4507378-A | POLYMERIZING MONOMER IN AQUEOUS DISPERSION CONTAINING PHOSPHATE, ANIONIC SURFACTANT AND COLORANT | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1985-03-26 | — | — | US | claimed |
| US-20120141176-A1 | METHOD FOR FORMING HIGH GLOSSY PRINTED MATTER | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-06-07 | — | — | US | disclosed |
| US-7547496-B2 | Image forming method and an image forming apparatus | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-06-16 | — | — | US | disclosed |
| US-7389082-B2 | Method and apparatus for forming an image having uniform glossiness | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2008-06-17 | — | — | US | disclosed |
| US-7183035-B2 | Image forming method | KONICA MINOLTA HOLDINGS, INC. (JP) | 2007-02-27 | — | — | US | disclosed |
| US-7157198-B2 | Toner for electrostatic latent image development and an image forming method | KONICA MINOLTA HOLDINGS, INC (JP) | 2007-01-02 | — | — | US | disclosed |
| US-20060239729-A1 | Image forming method and image forming apparatus | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. | 2006-10-26 | — | — | US | disclosed |
| EP-1715391-A2 | Image forming method and image forming apparatus for forming an image on a transparent substrate | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2006-10-25 | — | — | EP | disclosed |
| US-20060088776-A1 | Image forming method and an image forming apparatus | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2006-04-27 | — | — | US | disclosed |
| US-20050214665-A1 | Toner for electrostatic latent image development and an image forming method | KONICA MINOLTA HOLDINGS, INC. (JP) | 2005-09-29 | — | — | US | disclosed |
| US-20050208415-A1 | Image forming method | KONICA MINOLTA HOLDINGS, INC. (JP) | 2005-09-22 | — | — | US | disclosed |
| US-4507378-A | POLYMERIZING MONOMER IN AQUEOUS DISPERSION CONTAINING PHOSPHATE, ANIONIC SURFACTANT AND COLORANT | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1985-03-26 | — | — | US | disclosed |