Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetramethylammonium Ion SCHEMBL9641524 | 0.92 | BBOX1 (0.31) | — | |
| SCHEMBL7766438 | 0.83 | FFAR3 (0.33) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Potassium Ion SCHEMBL1025777 | 0.81 | FABP3 (0.32) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9515721 | 0.80 | CA2 (0.38) | — | |
| Lithium Ion SCHEMBL15646944 | 0.79 | FABP3 (0.32) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11970131 | 0.77 | GRIK1 (0.35) | — | |
| SCHEMBL165515 | 0.77 | GRIK1 (0.35) | — | |
| SCHEMBL28484871 | 0.67 | — | — | |
| SCHEMBL4887185 | 0.67 | — | — | |
| SCHEMBL6366970 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3242300-A | — | — | None | — | — | JP | disclosed |
| US-8617711-B2 | Single layer film and hydrophilic material comprising the same | MITSUI CHEMICALS, INC. (JP) | 2013-12-31 | — | — | US | disclosed |
| US-20090191373-A1 | Single Layer Film and Hydrophilic Material Comprising the Same | MITSUI CHEMICALS ,INC. | 2009-07-30 | — | — | US | disclosed |
| EP-1955782-A1 | SINGLE LAYER FILM AND HYDROPHILIC MATERIAL COMPOSED OF SAME | Mitsui Chemicals, Inc. (JP) | 2008-08-13 | — | — | EP | disclosed |
| EP-0950539-B1 | Thermal dye transfer receiving element | EASTMAN KODAK CO (US) | 2001-06-13 | — | — | EP | disclosed |
| US-5981431-A | A DYE IMAGE RECEIVING LAYER COMPRISING A WATER DISPERSABLE POLYESTER CONTAING A DIOL, A DIESTER AND A METALSULFONATE SALT CONTAINING DIACID | EASTMAN KODAK COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0950539-A1 | Thermal dye transfer receiving element | EASTMAN KODAK COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |
| EP-0381457-B1 | Method of treating polyester fibers, polyester fibers treated by said method, and composite composed of said polyester fibers and nitrile group-containing highly saturated copolymer rubber | NIPPON ZEON CO (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-5286783-A | Adhesive for bonding fibers to rubber | NIPPON ZEON CO., LTD. (JP) | 1994-02-15 | — | — | US | disclosed |
| US-5122397-A | Bonding embedded fibers to nitrile rubber by vulcanization; hoses, ribbed belts | NIPPON ZEON CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| JP-H03242300-A | RECLAMATION METHOD BY DREDGING | MITSUBISHI KASEI CORP | 1991-10-29 | — | — | JP | disclosed |
| EP-0381457-A2 | Method of treating polyester fibers, polyester fibers treated by said method, and composite composed of said polyester fibers and nitrile group-containing highly saturated copolymer rubber | NIPPON ZEON CO., LTD. (JP) | 1990-08-08 | — | — | EP | disclosed |