SCHEMBL4257430

SCHEMBL4257430

CCCC(Cl)OC(Cl)CCC

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28110168 0.87
SCHEMBL8380643 0.81 DNM1 (0.39) TSHR
SCHEMBL28973334 0.81 TSHR (0.38) TSHR
SCHEMBL8381370 0.79 OPRM1 (0.42) TSHR
SCHEMBL11492874 0.79 TSHR (0.55) TSHR
SCHEMBL2118847 0.78
SCHEMBL7136058 0.77 LMNA (0.48)
SCHEMBL8028653 0.77
SCHEMBL1683581 0.77 LMNA (0.42) TSHR
SCHEMBL8381592 0.77 LMNA (0.42) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119601777-A Electrolyte of perchloric solvent and electrochemical device 清华大学深圳国际研究生院 2025-03-11 CN claimed
CN-115975250-B Monodisperse polystyrene microsphere for glycosylated hemoglobin detection and preparation method thereof 无锡瑞格生物科技有限责任公司 2025-02-07 CN claimed
CN-109574160-B Preparation method of bipolar membrane with high lithium ion rejection rate 杭州水处理技术研究开发中心有限公司 2021-11-19 CN claimed
CN-106890572-A Dilute sulfuric acid electrodialysis concentrates film group device 杭州水处理技术研究开发中心有限公司 2017-06-27 CN claimed
CN-105622435-B Bipolar membrane device for preparing amino-1-propanol 建德蓝忻环境科技有限公司 2017-05-17 CN claimed
CN-105622435-A Bipolar membrane device for preparing amino-1-propanol JIANDE LANXIN ENV SCIENCE AND TECH CO LTD 2016-06-01 CN claimed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US claimed
US-12551570-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2026-02-17 US disclosed
US-12479927-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2025-11-25 US disclosed
US-20250213712-A1 ANTIBODY DRUG CONJUGATES COMPRISING CAMPTOTHECIN DERIVATIVES AND USES THEREOF INTOCELL, INC. (KR) 2025-07-03 US disclosed
US-12274898-B2 Substituted benzodiazepines as antibody-drug conjugates INTOCELL, INC. (KR) 2025-04-15 US disclosed
CN-119601777-A Electrolyte of perchloric solvent and electrochemical device 清华大学深圳国际研究生院 2025-03-11 CN disclosed
CN-115975250-B Monodisperse polystyrene microsphere for glycosylated hemoglobin detection and preparation method thereof 无锡瑞格生物科技有限责任公司 2025-02-07 CN disclosed
US-5136115-A BROMOALKYLATION OF AROMATIC COMPOUNDS ALBERMARLE CORPORATION 1992-08-04 US disclosed
EP-0369728-A1 Haloalkylation of aromatic compounds ETHYL CORPORATION (US) 1990-05-23 EP disclosed
EP-0367858-A1 Sulfide containing aliphatic epoxy resins THE DOW CHEMICAL COMPANY (US) 1990-05-16 EP disclosed
US-4072696-A 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity SYNTEX (U.S.A.) INC. (US) 1978-02-07 US disclosed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US disclosed
US-4048220-A CONJUGATED DIENE, HALOGENATING AGENT, CARBOXYLIC ACID, ACID SCM CORPORATION (US) 1977-09-13 US disclosed
US-3956500-A INSECTICIDES, NEMATOCIDES UNION CARBIDE CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213712-A1 ANTIBODY DRUG CONJUGATES COMPRISING CAMPTOTHECIN DERIVATIVES AND USES THEREOF CD47, TOP2A, SSB TSHR 1659/4885
US-12551570-B2 Compounds comprising cleavable linker and uses thereof FCGR2A, FCGR3B, FCGR1A TSHR 72/4885
US-12479927-B2 Compounds comprising cleavable linker and uses thereof VIP, ANTXR2, TNFRSF9 TSHR 82/4885
US-12274898-B2 Substituted benzodiazepines as antibody-drug conjugates GABRA3, GABRA6, GABRA4 TSHR 496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.