Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18433370 | 1.00 | TSHR (0.30) | TSHR | |
| SCHEMBL24495013 | 0.80 | TSHR (0.31) | TSHR | |
| SCHEMBL19033046 | 0.80 | TSHR (0.31) | TSHR | |
| SCHEMBL17173285 | 0.77 | TSHR (0.30) | TSHR | |
| SCHEMBL18354296 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL12566599 | 0.77 | — | — | |
| SCHEMBL21745868 | 0.77 | TSHR (0.30) | TSHR | |
| SCHEMBL22950621 | 0.77 | ALDH1A1 (0.30) | TSHR | |
| SCHEMBL20768162 | 0.77 | GRIN1 (0.32) | — | |
| SCHEMBL18135505 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11185853-B2 | Catalysts for polycarbonate production | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2021-11-30 | — | — | US | disclosed |
| US-10947252-B2 | Inhibitors of KEAP1-Nrf2 protein-protein interaction | JANSSEN PHARMACEUTICA NV (BE) | 2021-03-16 | — | — | US | disclosed |
| US-10662211-B2 | Catalysts and methods for polymer synthesis | Saurdi Aramco Technologies Company (SA) | 2020-05-26 | — | — | US | disclosed |
| US-10577346-B2 | Benzobicycloalkane derivatives, their preparation and pharmaceutical use thereof | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2020-03-03 | — | — | US | disclosed |
| US-20200055874-A1 | INHIBITORS OF KEAP1-Nrf2 PROTEIN-PROTEIN INTERACTION | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-20 | — | — | US | disclosed |
| US-10479861-B2 | Catalytic carbonylation catalysts and methods | NOVOMER, INC. (US) | 2019-11-19 | — | — | US | disclosed |
| US-20190256650-A1 | CATALYTIC CARBONYLATION CATALYSTS AND METHODS | NOVOMER, INC. (US) | 2019-08-22 | — | — | US | disclosed |
| US-20190193062-A1 | CATALYSTS FOR POLYCARBONATE PRODUCTION | ARAMCO PERFORMANCE MATERIALS LLC | 2019-06-27 | — | — | US | disclosed |
| US-20190161468-A1 | BENZODICYCLOALKANE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2019-05-30 | — | — | US | disclosed |
| US-10294250-B2 | Organoaminosilanes and methods for making same | VERSUM MATERIALS US, LLC (US) | 2019-05-21 | — | — | US | disclosed |
| EP-1284969-B1 | 3-(4,5-DIHYDROISOXAZOLE-5-YL)BENZOYLCYCLOHEXENONES AND THE USE THEREOF AS HERBICIDES | BASF AG (DE) | 2004-08-18 | — | — | EP | disclosed |
| EP-1240163-B1 | 3-(4,5-DIHYDROISOXAZOLE-5-YL)BENZOYLPYRAZOLE | BASF AG (DE) | 2004-03-31 | — | — | EP | disclosed |
| US-6645919-B1 | Nonphytotoxic to crops | BASF AKTIENGESELLSCHAFT (DE) | 2003-11-11 | — | — | US | disclosed |
| US-20030199699-A1 | 3-(4,5-Dihydroisoxaxol-5-yl)benzoylcyclohexenones and the use thereof as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | US | disclosed |
| US-20030100590-A1 | 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazole | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-29 | — | — | US | disclosed |
| EP-0915853-B1 | SUBSTITUTED 3-PHENYL PYRAZOLES | BASF AG (DE) | 2002-11-06 | — | — | EP | disclosed |
| US-6383986-B1 | USE AS HERBICIDES, DESICCANTS OR DEFOLIANTS AND PLANT SAFENING AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-07 | — | — | US | disclosed |
| US-20020025910-A1 | 3-heterocycly1 - substituted benzoyl derivatives | DEYN WOLFGANG VON (DE) | 2002-02-28 | — | — | US | disclosed |
| US-6197973-B1 | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |
| US-6165944-A | 4-(3-heterocyclyl-1-benzoyl) pyrazoles and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199699-A1 | 3-(4,5-Dihydroisoxaxol-5-yl)benzoylcyclohexenones and the use thereof as herbicides | CBR3, HDHD5, CBR1 | TSHR 2584/4885 |
| US-10662211-B2 | Catalysts and methods for polymer synthesis | PPOX, COASY, SOD1 | TSHR 4849/4885 |
| US-20020025910-A1 | 3-heterocycly1 - substituted benzoyl derivatives | CBR3, CBR1, RRS1 | TSHR 1631/4885 |
| US-20200055874-A1 | INHIBITORS OF KEAP1-Nrf2 PROTEIN-PROTEIN INTERACTION | KEAP1, NFE2L2, HMOX1 | TSHR 4787/4885 |
| US-10479861-B2 | Catalytic carbonylation catalysts and methods | CBR3, CBR1, EPHX2 | TSHR 4642/4885 |
| US-20190161468-A1 | BENZODICYCLOALKANE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | CYP3A7, CYP2A7, CYP2J2 | TSHR 4624/4885 |
| US-20190256650-A1 | CATALYTIC CARBONYLATION CATALYSTS AND METHODS | CBR3, CBR1, EPHX2 | TSHR 4642/4885 |
| US-20030100590-A1 | 3-(4,5-dihydroisoxazol-5-yl)benzoylpyrazole | CBR3, CBR1, DHX35 | TSHR 3034/4885 |
| US-10294250-B2 | Organoaminosilanes and methods for making same | DDAH1, IDUA, DDT | TSHR 3989/4885 |
| US-10577346-B2 | Benzobicycloalkane derivatives, their preparation and pharmaceutical use thereof | CYP3A7, UGT2B7, BDKRB1 | TSHR 4533/4885 |
| US-10947252-B2 | Inhibitors of KEAP1-Nrf2 protein-protein interaction | KEAP1, NFE2L2, HMOX1 | TSHR 4787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.