Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL21555662 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL317585 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL3277654 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL338469 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL136236 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL23012792 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL28062573 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL20668544 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL20668546 | 0.94 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL372478 | 0.94 | CA4 (0.84) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115295776-B | Antimony bismuth nickel alloy negative electrode material of lithium (potassium) ion battery and preparation method thereof | 吉林师范大学 | 2025-02-18 | — | — | CN | claimed |
| CN-118888768-B | Niobium-bismuth-based high-entropy alloy modified electrode for vanadium battery and preparation method thereof | 杭州德海艾科能源科技有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-118888768-A | Niobium-bismuth-based high-entropy alloy modified electrode for vanadium battery and preparation method thereof | 杭州德海艾科能源科技有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-117779130-B | Wafer electroplated tungsten alloy solution, preparation method and electroplating method | 昆山一鼎工业科技有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-117779011-B | Wafer electroless tungsten plating alloy solution, preparation method and electroless tungsten plating method | 昆山一鼎工业科技有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-117779130-A | Wafer electroplated tungsten alloy solution, preparation method and electroplating method | 昆山一鼎工业科技有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117779011-A | Wafer electroless tungsten plating alloy solution, preparation method and electroless tungsten plating method | 昆山一鼎工业科技有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117512591-A | Corrosion-resistant laser cladding layer and preparation method thereof | 芜湖点金机电科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-111229235-A | NiO/MgAl2O4Catalyst, preparation method and application thereof | 上海交通大学 | 2020-06-05 | — | — | CN | claimed |
| US-20260102796-A1 | Plasma Treatment With Liquid Cooling | PLASMATREAT GMBH (DE) | 2026-04-16 | — | — | US | disclosed |
| US-20260098222-A1 | HYDROCARBON UPGRADING PROCESS | UOP LLC (US) | 2026-04-09 | — | — | US | disclosed |
| US-20260098218-A1 | Hydrocarbon Upgrading Process Control | UOP LLC (US) | 2026-04-09 | — | — | US | disclosed |
| US-20260098220-A1 | HYDROCARBON UPGRADING PROCESS WITH RECYCLE | UOP LLC (US) | 2026-04-09 | — | — | US | disclosed |
| US-20250368899-A1 | BIOMASS OLEOTHERMAL LIQUEFACTION PROCESS | UOP LLC (US) | 2025-12-04 | — | — | US | disclosed |
| EP-1986804-A2 | PREPARATION OF UNIFORM NANOPARTICLES OF ULTRA-HIGH PURITY METAL OXIDES, MIXED METAL OXIDES, METALS, AND METAL ALLOYS | Brigham Young University (US) | 2008-11-05 | — | — | EP | disclosed |
| US-20080050630-A1 | Membrane-Electrode Assemblies for Fuel Cell, Their Manufacture and Use and Fuel Cells Incorporating Them | ACTA S.P.A. (IT) | 2008-02-28 | — | — | US | disclosed |
| US-20080032132-A1 | Preparation of uniform nanoparticles of ultra-high purity metal oxides, mixed metal oxides, metals, and metal alloys | BRIGHAM YOUNG UNIVERSITY | 2008-02-07 | — | — | US | disclosed |
| EP-1846974-A1 | MEMBRANE-ELECTRODE ASSEMBLIES FOR FUEL CELL, THEIR MANUFACTURE AND USE AND FUEL CELLS INCORPORATING THEM | Acta S.p.A. (IT) | 2007-10-24 | — | — | EP | disclosed |
| WO-2007098111-A2 | PREPARATION OF UNIFORM NANOPARTICLES OF ULTRA-HIGH PURITY METAL OXIDES, MIXED METAL OXIDES, METALS, AND METAL ALLOYS | BRIGHAM YOUNG UNIVERSITY (US) | 2007-08-30 | — | — | WO | disclosed |
| WO-2006074829-A1 | MEMBRANE-ELECTRODE ASSEMBLIES FOR FUEL CELL, THEIR MANUFACTURE AND USE AND FUEL CELLS INCORPORATING THEM | ACTA S.P.A. (IT) | 2006-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260102796-A1 | Plasma Treatment With Liquid Cooling | ZW10, WIZ, CASP14 | CA4 2392/4885ALDH1A1 4142/4885CASP1 330/4885 |
| US-20260098218-A1 | Hydrocarbon Upgrading Process Control | HAO2, SQLE, COXFA4 | CA4 2386/4885ALDH1A1 1360/4885CASP1 1400/4885 |
| US-20260098222-A1 | HYDROCARBON UPGRADING PROCESS | SQLE, HAO2, HMOX2 | CA4 1437/4885ALDH1A1 2479/4885CASP1 2648/4885 |
| US-20260098220-A1 | HYDROCARBON UPGRADING PROCESS WITH RECYCLE | SQLE, HAO2, COXFA4 | CA4 2333/4885ALDH1A1 2323/4885CASP1 2266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.