SCHEMBL43105

SCHEMBL43105

N[C@@H](Cc1ccccc1[N+](=O)[O-])C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.51
PKM P14618 1/20 0.51
PTGS1 P23219 1/20 0.51
XIAP P98170 1/20 0.51
SLC7A5 Q01650 1/20 0.51
NOS3 P29474 2/20 0.51
NOS1 P29475 2/20 0.51
NOS2 P35228 2/20 0.51
GRIA2 P42262 1/20 0.51
TSHR P16473 2/20 0.50
ALDH1A1 P00352 1/20 0.50
GRM8 O00222 1/20 0.48
GRM4 Q14833 1/20 0.48
PTPRA P18433 1/20 0.48
CYP1A2 P05177 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29429691 1.00 ALPI (0.51) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL43104 1.00 ALPI (0.51) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL8977587 1.00 ALPI (0.51) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL8126535 0.98 NOS3 (0.50) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL598438 0.86 GRM8 (0.48) NOS3NOS1NOS2GRIA2GRM8
SCHEMBL10416252 0.86 GRM8 (0.53) TSHRALDH1A1GRM8GRM4CYP1A2
SCHEMBL29500946 0.86 GRM8 (0.53) TSHRALDH1A1GRM8GRM4CYP1A2
SCHEMBL27977862 0.86 GRIA2 (0.45) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL13660654 0.85 PKM (0.53) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL3096665 0.85 ALDH1A1 (0.55) TSHRALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1777 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719486-A1 CONJUGATES AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
US-12577575-B2 Methods and compositions for promoting non-natural amino acid-containing protein production AMBRX, INC. (US) 2026-03-17 US claimed
EP-4644570-A1 HELICASE MUTANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN HIGH-THROUGHPUT SEQUENCING BGI Shenzhen (CN) 2025-11-05 EP claimed
US-12404512-B2 Method for optimizing antibody expression AMBRX, INC. (US) 2025-09-02 US claimed
EP-3788149-B1 A METHOD FOR OPTIMIZING ANTIBODY EXPRESSION AMBRX INC (US) 2025-08-27 EP claimed
US-12377294-B2 Anti-CD3 antibody folate bioconjugates and their uses AMBRX, INC. (US) 2025-08-05 US claimed
US-20250243472-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-07-31 US claimed
CN-119340400-B Composite current collector and preparation method thereof 扬州纳力新材料科技有限公司 2025-04-11 CN claimed
CN-119455003-A Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2025-02-18 CN claimed
CN-119455004-A Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2025-02-18 CN claimed
WO-2008031016-A2 HETEROCYCLIC LIGANDS FOR INTEGRIN IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-03-13 WO claimed
WO-2005122379-A9 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY UNIV CALIFORNIA (US) 2006-03-09 WO claimed
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-01-26 US claimed
WO-2005122379-A2 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-12-22 WO claimed
EP-0646596-B1 Nucleic acid binding oligomers having C-branches for therapy and diagnosis BAYER AG (DE) 1999-05-26 EP claimed
EP-0646595-B1 Nucleic acid binding oligomers having C-branches for therapy and diagnosis BAYER AG (DE) 1998-11-04 EP claimed
US-5623049-A FLEXIBLE ANTISENSE AGENTS COMPRISING OLIGONUCEOTIDES HAVING THE (DEOXY)RIBOSE BACKBONE REPLACED BY AN OLIGOPEPTIDE; PROTEASE- AND NUCLEASE-RESISTANT; VIRICIDES; ATTACHED TO CARRIERS ABLE TO PENETRATATE IN CELLS BAYER AKTIENGESELLSCHAFT (DE) 1997-04-22 US claimed
EP-0700928-A1 Nucleic acid-binding oligomers for therapy and diagnostics BAYER AG (DE) 1996-03-13 EP claimed
EP-0646595-A1 Nucleic acid binding oligomers having C-branches for therapy and diagnosis BAYER AG (DE) 1995-04-05 EP claimed
EP-0646596-A1 Nucleic acid binding oligomers having C-branches for therapy and diagnosis BAYER AG (DE) 1995-04-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy ITGA4, ITGB4, ITGA1 ALPI 3006/4885PKM 4240/4885PTGS1 3492/4885
US-12377294-B2 Anti-CD3 antibody folate bioconjugates and their uses FOLR2, FOLR1, CD2 ALPI 1217/4885PKM 4371/4885PTGS1 4505/4885
US-12577575-B2 Methods and compositions for promoting non-natural amino acid-containing protein production AARS1, NSUN3, UPF1 ALPI 2459/4885PKM 2865/4885PTGS1 4736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.