Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 4/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4313643 | 0.79 | CHEK1 (0.40) | DYRK1ACNR2CNR1GAALMNA | |
| SCHEMBL8017379 | 0.78 | MELK (0.43) | DYRK1ANPC1RAB9ACCR5L3MBTL1 | |
| SCHEMBL3240022 | 0.77 | L3MBTL1 (0.46) | DYRK1ABCHEALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL3232831 | 0.77 | OPRK1 (0.40) | GAAALDH1A1MAPK1 | |
| SCHEMBL3240305 | 0.76 | PDK1 (0.41) | PDK1BCHENPC1RAB9AL3MBTL1 | |
| SCHEMBL3245515 | 0.75 | CCR5 (0.42) | DYRK1AGAABCHEMAPTCCR5 | |
| SCHEMBL3241365 | 0.75 | ACHE (0.45) | PDK1CNR2CNR1KDM1AHDAC1 | |
| SCHEMBL3238195 | 0.74 | L3MBTL1 (0.36) | DYRK1AGAALMNABCHEALDH1A1 | |
| SCHEMBL3240064 | 0.74 | ROCK2 (0.39) | DYRK1AGAAALDH1A1MAPK1 | |
| SCHEMBL3237578 | 0.73 | DRD2 (0.45) | LMNAALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131958-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING TRIAZINE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2009-10-29 | — | — | WO | claimed |