Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434527 | 0.80 | ROCK2 (0.41) | ROCK2ROCK1ALDH1A1OPRK1MAPK1 | |
| SCHEMBL10083742 | 0.80 | ROCK2 (0.41) | ROCK2ROCK1ALDH1A1OPRK1MAPK1 | |
| Hydrochloric Acid SCHEMBL433923 | 0.80 | HSD11B1 (0.49) | L3MBTL1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL434036 | 0.79 | TP53 (0.54) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL431724 | 0.78 | L3MBTL1 (0.43) | L3MBTL1MEN1KMT2AROCK2ROCK1 | |
| SCHEMBL433860 | 0.78 | P2RX7 (0.55) | P2RX7TP53 | |
| SCHEMBL433922 | 0.77 | SMN1; SMN2 (0.53) | L3MBTL1MEN1KMT2AALDH1A1P2RX7 | |
| SCHEMBL432970 | 0.76 | CYP1A2 (0.44) | L3MBTL1MEN1KMT2AROCK2ROCK1 | |
| SCHEMBL433444 | 0.76 | SLC6A4 (0.47) | L3MBTL1MEN1KMT2AROCK2ROCK1 | |
| SCHEMBL435516 | 0.76 | L3MBTL1 (0.45) | L3MBTL1MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |