Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432970 | 0.89 | CYP1A2 (0.44) | CYP1A2CYP2C9HPGDMAPK1CYP2C19 | |
| Hydrochloric Acid SCHEMBL433923 | 0.86 | HSD11B1 (0.49) | CYP1A2CYP2C9HPGDMAPK1CYP2C19 | |
| SCHEMBL432937 | 0.83 | LMNA (0.44) | SLC6A4CYP1A2CYP2C9HPGDMAPK1 | |
| SCHEMBL434266 | 0.83 | MAPT (0.53) | CYP1A2CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL433922 | 0.82 | SMN1; SMN2 (0.53) | CYP1A2CYP2C9HPGDMAPK1CYP2C19 | |
| Hydrochloric Acid SCHEMBL433170 | 0.82 | SMN1; SMN2 (0.52) | CYP1A2CYP2C9HPGDMAPK1CYP2C19 | |
| Hydrochloric Acid SCHEMBL433028 | 0.81 | P2RX7 (0.42) | MEN1KMT2AMAPTP2RX7ROCK2 | |
| SCHEMBL433833 | 0.81 | OPRM1 (0.47) | MEN1KMT2AMAPTOPRM1OPRD1 | |
| SCHEMBL433030 | 0.81 | SLC6A3 (0.45) | MEN1KMT2AMAPTOPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL435636 | 0.80 | HTT (0.48) | MEN1KMT2AMAPTP2RX7L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |