Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL433923 | 0.83 | HSD11B1 (0.49) | TP53LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL433860 | 0.81 | P2RX7 (0.55) | TP53LMNA | |
| SCHEMBL433922 | 0.80 | SMN1; SMN2 (0.53) | TP53LMNAALDH1A1TSHRMEN1 | |
| SCHEMBL432970 | 0.79 | CYP1A2 (0.44) | TP53LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL434528 | 0.79 | L3MBTL1 (0.44) | TP53ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL433444 | 0.79 | SLC6A4 (0.47) | TP53LMNAOPRM1OPRD1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL433170 | 0.79 | SMN1; SMN2 (0.52) | TP53LMNAALDH1A1TSHRMEN1 | |
| SCHEMBL435915 | 0.78 | P2RX7 (0.60) | TP53LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL434266 | 0.78 | MAPT (0.53) | TP53LMNAOPRM1OPRD1ALDH1A1 | |
| SCHEMBL432937 | 0.78 | LMNA (0.44) | LMNAOPRM1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |