Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.49 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL433170 | 0.99 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL433923 | 0.94 | HSD11B1 (0.49) | SMN1; SMN2HTTMEN1KMT2ALMNA | |
| SCHEMBL433860 | 0.87 | P2RX7 (0.55) | LMNACYP2C9CYP2C19TRPA1P2RX7 | |
| SCHEMBL432970 | 0.85 | CYP1A2 (0.44) | SMN1; SMN2MEN1KMT2ALMNANPSR1 | |
| SCHEMBL435915 | 0.84 | P2RX7 (0.60) | SMN1; SMN2MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL435467 | 0.83 | ALDH1A1 (0.44) | MEN1KMT2ACYP1A2CYP2C9HPGD | |
| SCHEMBL434779 | 0.82 | POLB (0.52) | KMT2ALMNAMAPK1ALDH1A1P2RX7 | |
| SCHEMBL433444 | 0.82 | SLC6A4 (0.47) | SMN1; SMN2MEN1KMT2ALMNANPSR1 | |
| SCHEMBL432937 | 0.82 | LMNA (0.44) | MEN1KMT2ALMNACYP1A2CYP2C9 | |
| SCHEMBL434266 | 0.82 | MAPT (0.53) | SMN1; SMN2MEN1KMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |