Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4356470 | 0.92 | GPR119 (0.38) | GPR119SETD7L3MBTL1KMT2AMEN1 | |
| SCHEMBL4356808 | 0.91 | SETD7 (0.45) | POLBGPR119ROCK2HPGDSETD7 | |
| SCHEMBL4534628 | 0.90 | GPR119 (0.40) | GPR119 | |
| SCHEMBL4522943 | 0.88 | ALDH1A1 (0.36) | GPR119ROCK2HPGDKMT2AMEN1 | |
| SCHEMBL4353425 | 0.88 | SCD5 (0.36) | GPR119OTUD7BKCNH2KDM4EHRH3 | |
| SCHEMBL4350015 | 0.86 | GPR119 (0.41) | GPR119KMT2AMEN1KCNH2GAA | |
| SCHEMBL4353651 | 0.86 | KCNH2 (0.38) | ROCK2HPGDKMT2AMEN1KCNH2 | |
| SCHEMBL4350129 | 0.85 | KDM4E (0.37) | GPR119KDM4E | |
| SCHEMBL13586034 | 0.85 | ABL1 (0.46) | POLBGPR119ROCK2KMT2AMEN1 | |
| SCHEMBL4357683 | 0.84 | POLB (0.48) | POLBGPR119ROCK2HPGDL3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |