Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.35 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.35 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.35 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.35 |
| ▸ | P2RY4 known ✓ | P51582 | 1/20 | 0.33 |
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269781 | 0.82 | ALDH1A1 (0.42) | KDM4ETDP1MEN1KMT2ACA12 | |
| SCHEMBL500732 | 0.81 | ALDH1A1 (0.41) | KDM4ETDP1MEN1KMT2ACA12 | |
| SCHEMBL2231013 | 0.81 | ALDH1A1 (0.41) | KDM4ETDP1MEN1KMT2ACA12 | |
| SCHEMBL1609214 | 0.81 | ALDH1A1 (0.41) | KDM4ETDP1MEN1KMT2ACA12 | |
| SCHEMBL500880 | 0.81 | ALDH1A1 (0.41) | KDM4ETDP1MEN1KMT2ACA12 | |
| SCHEMBL6828054 | 0.81 | KDM4E (0.42) | KDM4ETDP1MEN1KMT2ALMNA | |
| SCHEMBL758179 | 0.81 | ALDH1A1 (0.41) | KDM4ETDP1MEN1KMT2ACA12 | |
| SCHEMBL9456750 | 0.79 | TPMT (0.39) | KDM4ETDP1MEN1KMT2ALMNA | |
| SCHEMBL672196 | 0.79 | NFKB1 (0.33) | TDP1CA1CA2CA4LMNA | |
| SCHEMBL5697529 | 0.77 | ALDH1A1 (0.35) | KDM4ETDP1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247153-B2 | Process for producing resin microparticles for a toner raw material | MITSUI CHEMICALS, INC. (JP) | 2012-08-21 | — | — | US | disclosed |
| US-20090020900-A1 | Process for Producing Resin Microparticles for a Toner Raw Material | MITSUI CHEMICALS, INC. (JP) | 2009-01-22 | — | — | US | disclosed |
| US-20070082285-A1 | Resin microparticle as raw material for toner, aqueous dispersed system thereof and toner | MITSUI CHEMICALS, INC. (JP) | 2007-04-12 | — | — | US | disclosed |
| EP-1679552-A1 | RESIN MICROPARTICLE AS RAW MATERIAL FOR TONER, DISPERSION SYSTEM THEREOF AND TONER | Mitsui Chemicals, Inc. (JP) | 2006-07-12 | — | — | EP | disclosed |