Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062505 | 0.90 | FAAH (0.32) | L3MBTL1LMNASMN1; SMN2ALOX5AP | |
| SCHEMBL4544148 | 0.88 | FAAH (0.36) | SLC26A4POLBL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL2005952 | 0.84 | SLC26A4 (0.37) | SLC26A4POLBLMNASMN1; SMN2ALOX5AP | |
| SCHEMBL2992472 | 0.82 | ALOX5AP (0.32) | ALOX5AP | |
| SCHEMBL2003876 | 0.82 | SLC26A4 (0.35) | SLC26A4POLBLMNASMN1; SMN2ALOX5AP | |
| SCHEMBL2004304 | 0.82 | FAAH (0.35) | SLC26A4POLBL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL2003138 | 0.82 | EDNRB (0.41) | SLC26A4POLBLMNASMN1; SMN2ALOX5AP | |
| SCHEMBL2009971 | 0.81 | L3MBTL1 (0.37) | SLC26A4POLBL3MBTL1LMNA | |
| SCHEMBL2002262 | 0.80 | PLA2G2A (0.37) | SLC26A4POLBLMNA | |
| SCHEMBL2005116 | 0.80 | LMNA (0.42) | SLC26A4POLBLMNASMN1; SMN2ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049520-A2 | INDOLE COMPOUNDS | Ironwood Pharmaceuticals, Inc. (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008019357-A2 | INDOLE COMPOUNDS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-02-14 | — | — | WO | disclosed |