Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 5/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456245 | 0.76 | TDP1 (0.44) | FBP1TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL15063992 | 0.73 | ALDH1A1 (0.35) | TDP1ALDH1A1MAPTPDK1TSHR | |
| SCHEMBL8361517 | 0.72 | TDP1 (0.58) | FBP1TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL125379 | 0.72 | GABRA1 (0.30) | — | |
| SCHEMBL1965156 | 0.70 | — | — | |
| SCHEMBL8091152 | 0.69 | PDK1 (0.42) | FBP1TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL15063970 | 0.69 | POLB (0.35) | FBP1MAPTPDK1POLBHTT | |
| SCHEMBL8348913 | 0.69 | NOS3 (0.36) | — | |
| SCHEMBL7779774 | 0.68 | TDP1 (0.52) | FBP1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL10662230 | 0.67 | TXNRD1 (0.43) | TDP1ALDH1A1LMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10736878-B2 | Treatment of organophosphate exposure with triptans | PFADENHAUER TINA (US) | 2020-08-11 | — | — | US | disclosed |
| US-20200188403-A1 | TREATMENT OF ORGANOPHOSPHATE EXPOSURE WITH OCINAPLON | HELTON DAVID (US) | 2020-06-18 | — | — | US | disclosed |
| US-20200085808-A1 | USE OF CYPROHEPTADINE TO TREAT ORGANOPHOSPHATE EXPOSURE | REPURPOSED THERAPEUTICS, INC. | 2020-03-19 | — | — | US | disclosed |
| US-10478438-B2 | Treatment of organophosphate exposure with ocinaplon | CENOMED, INC. | 2019-11-19 | — | — | US | disclosed |
| US-10398687-B2 | Use of cyproheptadine to treat organophosphate exposure | REPURPOSED THERAPEUTICS, INC. | 2019-09-03 | — | — | US | disclosed |
| EP-2568807-B1 | PHENOXYALKYL PYRIDINIUM OXIME THERAPEUTICS FOR TREATMENT OF ORGANOPHOSPHATE POISONING | UNIV MISSISSIPPI STATE (US) | 2018-07-11 | — | — | EP | disclosed |
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| US-20170258774-A1 | NOVEL OXIMES FOR REACTIVATING BUTYRYLCHOLINESTERASE | MISSISSIPPI STATE UNIVERSITY (US) | 2017-09-14 | — | — | US | disclosed |
| CN-106824277-A | The method of cerium Base Metal-organic framework material catalyzing hydrolysis organic compound phosphatide key | 中国科学院大连化学物理研究所 | 2017-06-13 | — | — | CN | disclosed |
| EP-3045450-A1 | INTERMEDIATE COMPOUNDS IN A PROCESS FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO., LTD. (JP) | 2016-07-20 | — | — | EP | disclosed |
| US-5792639-A | ENZYMES AS ANTIDOTES FOR ORGANOPHOSPHOROUS INSECTICIDE POISONING | HUMAN GENOME SCIENCES, INC. (US) | 1998-08-11 | — | — | US | disclosed |
| EP-0804591-A4 | SERUM PARAOXONASE | HUMAN GENOME SCIENCES INC (US) | 1998-07-29 | — | — | EP | disclosed |
| EP-0804591-A1 | SERUM PARAOXONASE | HUMAN GENOME SCIENCES, INC. (US) | 1997-11-05 | — | — | EP | disclosed |
| US-5650413-A | Derivatives of swainsonine, processes for their preparation and their use as therapeutic agents | GLYCODESIGN INC. (US) | 1997-07-22 | — | — | US | disclosed |
| US-5629193-A | Paraoxonase | HUMAN GENOME SCIENCES, INC. (US) | 1997-05-13 | — | — | US | disclosed |
| US-5595872-A | DNA SEQUENCES, CELLS AND EXPRESSION VECTORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-01-21 | — | — | US | disclosed |
| WO-1996001322-A1 | SERUM PARAOXONASE | HUMAN GENOME SCIENCES, INC. (US) | 1996-01-18 | — | — | WO | disclosed |
| US-4269820-A | MIXTURE WITH TOXIC HERBICIDES, PESTICIDES AND INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-05-26 | — | — | US | disclosed |
| US-4240802-A | PESTICIDES, HERBICIDES OR FUMIGANTS SOLUBLE IN SAID FUEL | NICHOLS WALLACE H JR | 1980-12-23 | — | — | US | disclosed |
| US-4173094-A | Method for treating ground surfaces with a toxic agent | NICHOLS WALLACE H JR | 1979-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200085808-A1 | USE OF CYPROHEPTADINE TO TREAT ORGANOPHOSPHATE EXPOSURE | BCHE, ACHE, DDT | FBP1 2822/4885TDP1 392/4885ALDH1A1 3156/4885 |
| US-20200188403-A1 | TREATMENT OF ORGANOPHOSPHATE EXPOSURE WITH OCINAPLON | PNPO, DDT, PON1 | FBP1 1490/4885TDP1 68/4885ALDH1A1 1282/4885 |
| US-10398687-B2 | Use of cyproheptadine to treat organophosphate exposure | BCHE, ACHE, DDT | FBP1 2822/4885TDP1 392/4885ALDH1A1 3156/4885 |
| US-20170258774-A1 | NOVEL OXIMES FOR REACTIVATING BUTYRYLCHOLINESTERASE | BCHE, ACHE, CHAT | FBP1 1119/4885TDP1 315/4885ALDH1A1 1183/4885 |
| US-10736878-B2 | Treatment of organophosphate exposure with triptans | DDT, THOP1, TPP1 | FBP1 3532/4885TDP1 54/4885ALDH1A1 1032/4885 |
| US-10478438-B2 | Treatment of organophosphate exposure with ocinaplon | PNPO, DDT, PON1 | FBP1 1490/4885TDP1 68/4885ALDH1A1 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.