Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.33 |
| ▸ | KMT5B | Q4FZB7 | 1/20 | 0.33 |
| ▸ | KMT5C | Q86Y97 | 1/20 | 0.33 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441831 | 0.82 | ALDH1A1 (0.46) | ACHECYP3A4ALDH1A1PDGFRBTSHR | |
| SCHEMBL438598 | 0.82 | ACHE (0.41) | ACHEDYRK1AMAPK13CDK1PIM1 | |
| SCHEMBL439464 | 0.78 | NR4A2 (0.55) | ACHENR4A2SOS2 | |
| SCHEMBL437503 | 0.76 | TNF (0.35) | ACHEALDH1A1DHFR | |
| SCHEMBL442268 | 0.75 | ACHE (0.46) | ACHEPIM1CYP3A4ALDH1A1 | |
| SCHEMBL440082 | 0.75 | LMNA (0.47) | ACHEALDH1A1TSHR | |
| SCHEMBL438239 | 0.75 | ACHE (0.46) | ACHENR4A2SOS2 | |
| SCHEMBL438932 | 0.75 | ACHE (0.46) | ACHENR4A2SOS2 | |
| SCHEMBL439645 | 0.75 | ACHE (0.46) | ACHENR4A2 | |
| SCHEMBL442137 | 0.75 | HTT (0.49) | ACHEPIM1PIM3CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |