Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396410 | 0.92 | L3MBTL1 (0.40) | FAAHKDM4EALDH1A1 | |
| SCHEMBL4401571 | 0.92 | HPGDS (0.39) | HTR7HTR1A | |
| SCHEMBL4396992 | 0.90 | KMT2A (0.41) | FAAHKDM4EKMT2AMEN1 | |
| SCHEMBL4406835 | 0.90 | CHRM3 (0.40) | FAAH | |
| SCHEMBL4394199 | 0.90 | CHRM3 (0.41) | HTR7HTR1AFAAH | |
| SCHEMBL4396457 | 0.89 | HRH3 (0.42) | HTR7HTR1AFAAHKDM4ESMN1; SMN2 | |
| SCHEMBL4410349 | 0.89 | HRH3 (0.42) | HTR7HTR1AFAAHKDM4ESMN1; SMN2 | |
| SCHEMBL4396593 | 0.89 | CHRM3 (0.42) | — | |
| SCHEMBL4405673 | 0.88 | CHRM3 (0.42) | — | |
| SCHEMBL4405570 | 0.87 | TLR7 (0.43) | KDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |