Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396410 | 0.91 | L3MBTL1 (0.40) | DYRK1AWNT1FAAH | |
| SCHEMBL4396337 | 0.90 | HTR7 (0.43) | HTR7HTR1AFAAH | |
| SCHEMBL4396992 | 0.89 | KMT2A (0.41) | CHRM3DYRK1AACKR3HTR4FAAH | |
| SCHEMBL4396457 | 0.88 | HRH3 (0.42) | HTR7HTR1AFAAH | |
| SCHEMBL4410349 | 0.88 | HRH3 (0.42) | HTR7HTR1AFAAH | |
| SCHEMBL4401571 | 0.87 | HPGDS (0.39) | DYRK1AWNT1HTR7HTR1AHPGDS | |
| SCHEMBL4406835 | 0.87 | CHRM3 (0.40) | CHRM3DYRK1AWNT1FAAH | |
| SCHEMBL4405570 | 0.86 | TLR7 (0.43) | RAD52DYRK1AHTR4 | |
| SCHEMBL914333 | 0.85 | KDM4E (0.43) | CHRM3RAD52DYRK1AWNT1ACKR3 | |
| SCHEMBL4405673 | 0.85 | CHRM3 (0.42) | CHRM3DYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |