Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | WNT1 | P04628 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396337 | 0.92 | HTR7 (0.43) | HTR1AHTR7 | |
| SCHEMBL4396410 | 0.90 | L3MBTL1 (0.40) | WNT1DYRK1A | |
| SCHEMBL4406835 | 0.89 | CHRM3 (0.40) | WNT1DYRK1ASIGMAR1 | |
| SCHEMBL4396992 | 0.88 | KMT2A (0.41) | DYRK1ASIGMAR1 | |
| SCHEMBL4394199 | 0.87 | CHRM3 (0.41) | HPGDSWNT1DYRK1AHTR1AHTR7 | |
| SCHEMBL4396457 | 0.86 | HRH3 (0.42) | HTR1AHTR7 | |
| SCHEMBL4410349 | 0.86 | HRH3 (0.42) | HTR1AHTR7 | |
| SCHEMBL4405673 | 0.86 | CHRM3 (0.42) | WNT1DYRK1A | |
| SCHEMBL4396957 | 0.85 | TLR9 (0.42) | HPGDSWNT1DYRK1ASIGMAR1HTR7 | |
| SCHEMBL4396593 | 0.85 | CHRM3 (0.42) | WNT1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |