Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401901 | 0.87 | HTR4 (0.46) | KDM4EHRH4HTR4SIGMAR1ALDH1A1 | |
| SCHEMBL4396337 | 0.87 | HTR7 (0.43) | KDM4ELMNAFAAHALDH1A1SMN1; SMN2 | |
| SCHEMBL4404430 | 0.85 | HTR4 (0.37) | LMNAHTR4PARP1 | |
| SCHEMBL4409097 | 0.85 | CCR8 (0.44) | FAAHALDH1A1SMN1; SMN2 | |
| SCHEMBL4405558 | 0.85 | HTR4 (0.39) | KDM4EHTR4SMN1; SMN2PARP1 | |
| SCHEMBL4401571 | 0.84 | HPGDS (0.39) | SIGMAR1 | |
| SCHEMBL4396410 | 0.84 | L3MBTL1 (0.40) | KDM4EFAAHALDH1A1 | |
| SCHEMBL4400739 | 0.84 | GUCY1B2 (0.37) | MAPTKDM4ELMNAHTR4PARP1 | |
| SCHEMBL4405631 | 0.84 | SSTR4 (0.40) | LMNAHTR4 | |
| SCHEMBL4396602 | 0.84 | SRD5A2 (0.47) | TMEM97FAAHSIGMAR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |