Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4417093 | 0.88 | MAPT (0.43) | NCEH1FAAHALDH1A1HSD17B10HTR2A | |
| SCHEMBL4423191 | 0.87 | NCEH1 (0.41) | NCEH1ALDH1A1HSD17B10HTR2AHTR2C | |
| SCHEMBL4419939 | 0.86 | HTR2A (0.42) | NCEH1FAAHALDH1A1HSD17B10HTR2A | |
| SCHEMBL4422341 | 0.85 | NCEH1 (0.43) | NCEH1HTR1AALDH1A1HSD17B10HTR2A | |
| SCHEMBL3925346 | 0.85 | HTR2A (0.49) | FAAHP2RX7ALDH1A1HTR2AHTR2C | |
| SCHEMBL4425475 | 0.84 | MGLL (0.38) | NCEH1HTR1AALDH1A1HSD17B10HTR2A | |
| SCHEMBL4418725 | 0.83 | HTR2A (0.46) | FAAHHTR2AHTR2CSLC6A4 | |
| SCHEMBL4423695 | 0.83 | HTR2A (0.41) | NCEH1ALDH1A1HSD17B10HTR2AHTR2C | |
| SCHEMBL4426602 | 0.82 | PLA2G2A (0.42) | ALDH1A1HSD17B10ACHE | |
| SCHEMBL5043850 | 0.81 | NCEH1 (0.41) | NCEH1FAAHHTR1AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583742-B1 | CB 1 RECEPTOUR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2009-12-02 | — | — | EP | claimed |