Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4417093 | 0.91 | MAPT (0.43) | NCEH1HTR2AHTR2CSLC6A4TSHR | |
| SCHEMBL4418725 | 0.89 | HTR2A (0.46) | HTR2AHTR2CSLC6A4 | |
| SCHEMBL4423695 | 0.89 | HTR2A (0.41) | NCEH1HTR2AHTR2CSLC6A4ALDH1A1 | |
| SCHEMBL4419939 | 0.89 | HTR2A (0.42) | NCEH1HTR2AHTR2CSLC6A4ALDH1A1 | |
| SCHEMBL4417423 | 0.88 | MGLL (0.43) | HTR2AHTR2CSLC6A4TP53ALDH1A1 | |
| SCHEMBL4417700 | 0.87 | NCEH1 (0.42) | NCEH1HTR2AHTR2CSLC6A4TP53 | |
| SCHEMBL4425227 | 0.87 | CNR1 (0.41) | NCEH1HTR2AHTR2CSLC6A4ALDH1A1 | |
| SCHEMBL4423636 | 0.86 | ALDH1A1 (0.47) | HTR2AHTR2CSLC6A4ALDH1A1ACHE | |
| SCHEMBL4425161 | 0.85 | RAB9A (0.43) | HTR2AHTR2CSLC6A4TSHRALDH1A1 | |
| SCHEMBL4419276 | 0.85 | ACHE (0.39) | NCEH1HTR2AHTR2CSLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583742-B1 | CB 1 RECEPTOUR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2009-12-02 | — | — | EP | claimed |