Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423695 | 0.88 | HTR2A (0.41) | MGLLALDH1A1HSD17B10HTR2AHTR2C | |
| SCHEMBL4422341 | 0.85 | NCEH1 (0.43) | MGLLALDH1A1HSD17B10HTR2AHTR2C | |
| SCHEMBL3928010 | 0.84 | HTR2A (0.51) | ALDH1A1HTR2AHTR2CSLC6A4KMT2A | |
| SCHEMBL4417700 | 0.84 | NCEH1 (0.42) | ALDH1A1HSD17B10HTR2AHTR2CSLC6A4 | |
| SCHEMBL4426602 | 0.83 | PLA2G2A (0.42) | MGLLALDH1A1HSD17B10ACHE | |
| SCHEMBL4418725 | 0.83 | HTR2A (0.46) | HTR2AHTR2CSLC6A4 | |
| SCHEMBL4417093 | 0.83 | MAPT (0.43) | MGLLALDH1A1HSD17B10HTR2AHTR2C | |
| SCHEMBL4425227 | 0.82 | CNR1 (0.41) | MGLLALDH1A1HSD17B10HTR2AHTR2C | |
| SCHEMBL4422250 | 0.82 | HTR2A (0.46) | MGLLALDH1A1HSD17B10HTR2AHTR2C | |
| SCHEMBL4423636 | 0.82 | ALDH1A1 (0.47) | MGLLALDH1A1HTR2AHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583742-B1 | CB 1 RECEPTOUR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2009-12-02 | — | — | EP | claimed |