Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 12/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | STK4 | Q13043 | 1/20 | 0.34 |
| ▸ | STK3 | Q13188 | 1/20 | 0.34 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.34 |
| ▸ | STK26 | Q9P289 | 1/20 | 0.34 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4412660 | 0.81 | ALDH1A1 (0.37) | KMT2ANPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL4414871 | 0.73 | MAPT (0.45) | MEN1KMT2AKDRABL1EGFR | |
| SCHEMBL4428827 | 0.71 | EGFR (0.50) | KDREGFRNPC1RAB9A | |
| SCHEMBL4417948 | 0.71 | GAA (0.43) | PIK3CACDK2GSK3AGSK3BMEN1 | |
| SCHEMBL4427810 | 0.70 | EGFR (0.45) | PIK3CGPIK3CAPIK3CDPIK3CBMEN1 | |
| SCHEMBL4414428 | 0.70 | EGFR (0.47) | ABL1EGFRHTTRAB9ASMN1; SMN2 | |
| SCHEMBL4411564 | 0.70 | CDC7 (0.49) | CDK2GSK3BSTK3MEN1KMT2A | |
| SCHEMBL4413885 | 0.70 | FYN (0.46) | GSK3AGSK3BMEN1KMT2AKDR | |
| SCHEMBL4414311 | 0.70 | EGFR (0.53) | MEN1KMT2AKDREGFRNPC1 | |
| SCHEMBL4417430 | 0.68 | BRAF (0.41) | MEN1KMT2AEGFRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601713-B2 | Kinase inhibitors and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2009-10-13 | — | — | US | claimed |