Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 12/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28255977 | 0.86 | MAPT (0.45) | MAPTHSD17B10L3MBTL1MEN1KMT2A | |
| SCHEMBL1263340 | 0.82 | CRBN (0.44) | MAPTHSD17B10L3MBTL1MEN1KMT2A | |
| SCHEMBL11049824 | 0.80 | MAPT (0.42) | MAPTHSD17B10L3MBTL1MEN1KMT2A | |
| SCHEMBL9008187 | 0.75 | MAPT (0.43) | MAPTHSD17B10L3MBTL1MEN1KMT2A | |
| SCHEMBL8428770 | 0.70 | LMNA (0.36) | MAPTHSD17B10L3MBTL1MEN1KMT2A | |
| SCHEMBL6652471 | 0.68 | YTHDF2 (0.40) | MAPTHSD17B10L3MBTL1MEN1KMT2A | |
| SCHEMBL29094161 | 0.67 | MAPT (0.33) | MAPTHSD17B10L3MBTL1MEN1KMT2A | |
| SCHEMBL11741115 | 0.65 | MEN1 (0.43) | MAPTHSD17B10L3MBTL1MEN1KMT2A | |
| Chloromethane SCHEMBL27796101 | 0.63 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL23602292 | 0.63 | MAPT (0.39) | MAPTHSD17B10L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912057-A | A method of barbituric acid derivatives are replaced by amine catalytic air oxidation green syt 5- hydroxyl -5- alkyl two | 河南大学 | 2018-11-30 | — | — | CN | claimed |
| EP-2081576-A2 | METHOD OF IMPROVING BIOAVAILABILITY FOR NON-SEDATING BARBITURATES | Taro Pharmaceuticals North America, Inc. (KY) | 2009-07-29 | — | — | EP | claimed |
| WO-2008066704-A2 | METHOD OF IMPROVING BIOAVAILABILITY FOR NON-SEDATING BARBITURATES | TARO PHARMACEUTICALS NORTH AMERICA, INC. (KY) | 2008-06-05 | — | — | WO | claimed |
| US-20080132529-A1 | Method of improving bioavailability for non-sedating barbiturates | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-06-05 | — | — | US | claimed |
| CN-1291720-C | Non-sedating barbituric acid derivatives | TARO PHARMA IND (IL) | 2006-12-27 | — | — | CN | claimed |
| EP-1485101-A4 | NON-SEDATING BARBITURIC ACID DERIVATIVES | TARO PHARMA IND (IL) | 2006-04-12 | — | — | EP | claimed |
| US-6939873-B2 | Non-sedating barbituric acid derivatives | TARO PHARMACEUTICALS INDUSTRIES LIMITED (IL) | 2005-09-06 | — | — | US | claimed |
| CN-1625401-A | Non-sedating barbituric acid derivatives | TARO PHARMA IND (IL) | 2005-06-08 | — | — | CN | claimed |
| EP-1485101-A1 | NON-SEDATING BARBITURIC ACID DERIVATIVES | Taro Pharmaceutical Industries Limited (IL) | 2004-12-15 | — | — | EP | claimed |
| US-20030187005-A1 | Non-sedating barbituric acid derivatives | TARO PHARMACEUTICAL INDUSTRIES LTD. | 2003-10-02 | — | — | US | claimed |
| WO-2003063872-A1 | NON-SEDATING BARBITURIC ACID DERIVATIVES | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-08-07 | — | — | WO | claimed |
| CN-114144487-A | Method and article for disposing adhesive onto a substrate | 3M创新有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-108912057-A | A method of barbituric acid derivatives are replaced by amine catalytic air oxidation green syt 5- hydroxyl -5- alkyl two | 河南大学 | 2018-11-30 | — | — | CN | disclosed |
| EP-2081576-A2 | METHOD OF IMPROVING BIOAVAILABILITY FOR NON-SEDATING BARBITURATES | Taro Pharmaceuticals North America, Inc. (KY) | 2009-07-29 | — | — | EP | disclosed |
| US-20080132529-A1 | Method of improving bioavailability for non-sedating barbiturates | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-06-05 | — | — | US | disclosed |
| US-6939873-B2 | Non-sedating barbituric acid derivatives | TARO PHARMACEUTICALS INDUSTRIES LIMITED (IL) | 2005-09-06 | — | — | US | disclosed |
| CN-1625401-A | Non-sedating barbituric acid derivatives | TARO PHARMA IND (IL) | 2005-06-08 | — | — | CN | disclosed |
| EP-1485101-A1 | NON-SEDATING BARBITURIC ACID DERIVATIVES | Taro Pharmaceutical Industries Limited (IL) | 2004-12-15 | — | — | EP | disclosed |
| US-20030187005-A1 | Non-sedating barbituric acid derivatives | TARO PHARMACEUTICAL INDUSTRIES LTD. | 2003-10-02 | — | — | US | disclosed |
| WO-2003063872-A1 | NON-SEDATING BARBITURIC ACID DERIVATIVES | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132529-A1 | Method of improving bioavailability for non-sedating barbiturates | MTNR1B, GABRB3, GABBR1 | MAPT 1872/4885HSD17B10 914/4885L3MBTL1 1822/4885 |
| US-20030187005-A1 | Non-sedating barbituric acid derivatives | GABRA5, GABRA1, GABRA3 | MAPT 647/4885HSD17B10 1126/4885L3MBTL1 1783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.