Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR known ✓ | P00374 | 1/20 | 0.38 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.37 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.37 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.36 |
| ▸ | PPARG known ✓ | P37231 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.38 |
| ▸ | HNF4A | P41235 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL9641315 | 0.95 | KDM4E (0.42) | KDM4EPOLBTDP1ALDH1A1HPGD | |
| SCHEMBL6261783 | 0.78 | CA2 (0.50) | KDM4EPOLBTDP1ALDH1A1HPGD | |
| SCHEMBL28480929 | 0.78 | CA1 (0.50) | KDM4EPOLBTDP1ALDH1A1HPGD | |
| SCHEMBL38652123 | 0.78 | CA2 (0.50) | KDM4EPOLBTDP1ALDH1A1HPGD | |
| Pyromellitic Acid SCHEMBL6263960 | 0.78 | KDM4E (0.48) | KDM4EPOLBTDP1ALDH1A1HPGD | |
| SCHEMBL2809848 | 0.76 | KDM4E (0.70) | KDM4EPOLBTDP1ALDH1A1HPGD | |
| SCHEMBL4446245 | 0.76 | CA1 (0.52) | KDM4EPOLBTDP1ALDH1A1HPGD | |
| SCHEMBL22206255 | 0.76 | KDM4E (0.39) | KDM4EPOLBTDP1ALDH1A1HPGD | |
| SCHEMBL6693861 | 0.76 | TDP1 (0.47) | KDM4EPOLBTDP1ALDH1A1HPGD | |
| SCHEMBL8679191 | 0.76 | CA1 (0.52) | KDM4EPOLBTDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1224330-A | — | — | None | — | — | JP | disclosed |
| CN-114084994-B | Treatment method of BPDA series acidified waste brine | 河北海力香料股份有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-114084994-A | Treatment method of BPDA series acidified waste brine | 河北海力香料股份有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-113717136-A | High-yield green safe synthesis method of 3,3',4,4' -biphenyl tetracarboxylic dianhydride | 江西师范大学 | 2021-11-30 | — | — | CN | disclosed |
| US-20090048462-A1 | Method for producing biphenyltetracarboxylic acid | JFE CHEMICAL CORPORATION (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1801092-A1 | PROCESS FOR PRODUCING BIPHENYLTETRACARBOXYLIC ACID | JFE Chemical Corporation (JP) | 2007-06-27 | — | — | EP | disclosed |
| EP-0421046-B1 | Process for producing highly pure 3,3',4,4' - biphenyltetra- carboxylic acid or dianhydride thereof | HITACHI LTD (JP) | 1995-06-14 | — | — | EP | disclosed |
| US-5047560-A | Process for producing highly pure 3,3',4,4'-biphenyltetracarboxylic acid or dianhydride thereof | HITACHI, LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0421046-A1 | Process for producing highly pure 3,3',4,4' - biphenyltetra- carboxylic acid or dianhydride thereof | HITACHI, LTD. (JP) | 1991-04-10 | — | — | EP | disclosed |
| JP-H01224330-A | DIMERIZATION OF AROMATIC HALOGEN COMPOUND | MITSUBISHI KASEI CORP | 1989-09-07 | — | — | JP | disclosed |
| US-4727185-A | Process for preparation of 3,3',4,4'-biphenyltetracarboxylic acid salts | HITACHI, LTD. (JP) | 1988-02-23 | — | — | US | disclosed |