SCHEMBL444989

SCHEMBL444989

Nc1ccccc1C(=O)OC1=CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.47
HSD17B10 Q99714 9/20 0.47
CFTR P13569 1/20 0.47
KDM4E B2RXH2 6/20 0.43
TSHR P16473 3/20 0.43
POLB P06746 2/20 0.43
HPGD P15428 4/20 0.43
GLA P06280 2/20 0.43
RAB9A P51151 4/20 0.40
NPC1 O15118 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
HIF1A Q16665 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NFKB1 P19838 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8140023 0.89 KDM4E (0.39) ALDH1A1HSD17B10KDM4ETSHRPOLB
SCHEMBL5824031 0.83 HSD17B10 (0.51) ALDH1A1HSD17B10KDM4ETSHRPOLB
SCHEMBL20503234 0.82 KMT2A (0.47) ALDH1A1RAB9ANPC1CYP3A4MEN1
SCHEMBL6353529 0.78 KMT2A (0.51) ALDH1A1HSD17B10TSHRSMN1; SMN2TDP1
SCHEMBL30445691 0.77 KMT2A (0.44) ALDH1A1RAB9ANPC1CYP3A4MEN1
SCHEMBL8138563 0.75 KMT2A (0.39) ALDH1A1HPGDRAB9ANPC1SMN1; SMN2
SCHEMBL6430893 0.73 ALDH1A1 (0.60) ALDH1A1HSD17B10CFTRKDM4ETSHR
SCHEMBL8132876 0.73 MAPK1 (0.41) ALDH1A1KDM4EPOLBHPGDRAB9A
SCHEMBL10663480 0.73 ALDH1A1 (0.33) ALDH1A1HSD17B10KDM4ETSHRHPGD
SCHEMBL9341204 0.72 KMT2A (0.49) ALDH1A1TSHRSMN1; SMN2L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025073990-A1 SPF BOOSTER FOR SUNSCREEN COMPOSITION OXFORD UNIVERSITY INOVATION LTD. (GB) 2025-04-10 WO disclosed
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents COLABS INT'L CORP. (US) 2024-03-28 US disclosed
US-11839674-B2 Compositions comprising silicon dioxide-based particles including one or more agents CoLabs International Corporation (US) 2023-12-12 US disclosed
US-11752086-B2 Topical formulations and methods MYOCEPT INC. (US) 2023-09-12 US disclosed
US-11724134-B2 Compositions containing a cellulose derived capsule with a sunscreen active agent CoLabs International Corporation (US) 2023-08-15 US disclosed
CN-114685851-A Photostable compositions comprising p-alkoxyphenyl substituted acrylic Acid (APP) derivatives 浩思特美容与个人护理创新公司 2022-07-01 CN disclosed
US-20210338558-A1 USE OF COLLAGEN BINDING DOMAINS TO DELIVER PRODUCTS TO SKIN FABIUS BIOTECHNOLOGY (US) 2021-11-04 US disclosed
CN-107847422-B Photostable compositions comprising p-alkoxyphenyl substituted acrylic Acid (APP) copolymer derivatives 浩思特美容与个人护理创新公司 2020-11-27 CN disclosed
WO-2020068665-A1 USE OF COLLAGEN BINDING DOMAINS TO DELIVER PRODUCTS TO SKIN FABIUS BIOTECHNOLOGY (US) 2020-04-02 WO disclosed
WO-2018148338-A1 TOPICAL FORMULATIONS AND METHODS PETERS LARS ERIK (US) 2018-08-16 WO disclosed
WO-2003070161-A2 EMULSIFIED SKIN CARE COMPOSITION CONTAINING SALICYLIC ACID, LANOLIN OIL, AND PROPYLENE GLYCOL ALWYN COMPANY, INC. (US) 2003-08-28 WO disclosed
US-20030157137-A1 Emulsified skin care composition containing salicylic acid, lanolin oil, and propylene glycol ALWYN COMPANY, INC. 2003-08-21 US disclosed
US-20030147968-A1 Allantoin-containing preparations for administration as gels and aerosols ALWYN COMPANY, INC. 2003-08-07 US disclosed
WO-2003053369-A1 ALLANTOIN-CONTAINING PREPARATIONS FOR ADMINISTRATION AS GELS AND AEROSOLS ALWYN COMPANY, INC. (US) 2003-07-03 WO disclosed
WO-2003041688-A1 METHODS FOR TREATMENT OF INFLAMMATORY DISEASES ALWYN COMPANY, INC. (US) 2003-05-22 WO disclosed
WO-2003041651-A2 ALLATOIN-CONTAINING SKIN CREAM ALWYN COMPANY, INC. (US) 2003-05-22 WO disclosed
US-20020054895-A1 And at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water; skin protectants ALWYN COMPANY, INC. 2002-05-09 US disclosed
US-20020055531-A1 Methods for treatment of inflammatory diseases SWEEN, MAURICE ALWYN 2002-05-09 US disclosed
US-6376557-B1 TRANSDERMAL SUPPLYING ZAVERI CHANDA BHUWALKA (US) 2002-04-23 US disclosed
WO-2001068107-A1 HAIR RESTORATION FORMULATION ZAVERI CHANDA BHUWALKA (US) 2001-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11724134-B2 Compositions containing a cellulose derived capsule with a sunscreen active agent CUTA, ACMSD, TYR ALDH1A1 463/4885HSD17B10 1495/4885CFTR 4286/4885
US-20210338558-A1 USE OF COLLAGEN BINDING DOMAINS TO DELIVER PRODUCTS TO SKIN COL14A1, COL2A1, COL1A1 ALDH1A1 3422/4885HSD17B10 2810/4885CFTR 2540/4885
US-11752086-B2 Topical formulations and methods KRT18, ANXA3, VIP ALDH1A1 4831/4885HSD17B10 2793/4885CFTR 522/4885
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents MSN, LIPE, CUTA ALDH1A1 1189/4885HSD17B10 3508/4885CFTR 3332/4885
US-11839674-B2 Compositions comprising silicon dioxide-based particles including one or more agents MSN, LIPE, CUTA ALDH1A1 1278/4885HSD17B10 3630/4885CFTR 3393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.