Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.44 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.44 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.64 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27518731 | 1.00 | MEN1 (0.64) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL11511436 | 0.93 | MEN1 (0.61) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL28437698 | 0.89 | MEN1 (0.55) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL9393646 | 0.88 | MEN1 (0.53) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL2235313 | 0.87 | MAPK1 (0.64) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL340519 | 0.87 | MAPK1 (0.64) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| Potassium Ion SCHEMBL29760204 | 0.87 | MEN1 (0.55) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL5490689 | 0.86 | MEN1 (0.69) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL4955027 | 0.86 | MEN1 (0.69) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL11254222 | 0.85 | ALDH1A1 (0.85) | MEN1USP2ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531298-B2 | Silver halide color photosensitive material | FUJIFILM CORPORATION (JP) | 2009-05-12 | — | — | US | disclosed |
| US-7195864-B2 | Silver halide photographic light-sensitive material and aqueous coating composition | FUJI PHOTO FILM CO., LTD. (JP) | 2007-03-27 | — | — | US | disclosed |
| EP-1750173-A1 | Silver halide photosensitive material and packaged body containing the same | Fuji Photo Film Co., Ltd. (JP) | 2007-02-07 | — | — | EP | disclosed |
| US-7122299-B2 | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2006-10-17 | — | — | US | disclosed |
| US-20050142505-A1 | Silver halide photographic light-sensitive material and aqueous coating composition | FUJI PHOTO FILM CO., LTD. | 2005-06-30 | — | — | US | disclosed |
| US-20050106513-A1 | Blue, green, red-sensitive layer and a non-light-sensitive layer on a support and a silver halide color photosensitive material of a fluorinated diester metal salt; capable of undergoing a one-electron oxidation to a one-electron oxidation product capable of releasing electrons and forming a bond | FUJI PHOTO FILM CO., LTD. | 2005-05-19 | — | — | US | disclosed |
| US-20050032008-A1 | Silver halide color photosensitive material | FUJI PHOTO FILM CO., LTD. | 2005-02-10 | — | — | US | disclosed |
| US-6844146-B2 | Silver halide color photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2005-01-18 | — | — | US | disclosed |
| US-20040185392-A1 | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. | 2004-09-23 | — | — | US | disclosed |
| US-20030235793-A1 | SILVER HALIDE PHOTOGRAPHIC PHOTOSENSITIVE MATERIAL | FUJIFILM CORPORATION (JP) | 2003-12-25 | — | — | US | disclosed |
| US-5206134-A | Adding simultaneously silver nitrate and metal iodide solutions or adding fine particles of silver iodide and/or silver iodobromide, producing grains with low surface iodide content | FUJI PHOTO FILM CO., LTD. (JP) | 1993-04-27 | — | — | US | disclosed |
| EP-0528435-A1 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |
| US-5118600-A | Having improved developability, sensitivity/fogging ratio and pressure characteristics | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| US-5108885-A | Antistatic agents | FUJI PHOTO FILM CO., LTD. (JP) | 1992-04-28 | — | — | US | disclosed |
| EP-0475191-A2 | Method for producing silver halide photographic emulsion | FUJI PHOTO FILM CO., LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| EP-0438135-A1 | Silver halide photographic photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-24 | — | — | EP | disclosed |
| US-5028520-A | Polyhydroxybenzene Compound, Reduction of Reflection Index, Crossover Elimination | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| US-5015562-A | Light-sensitive silver halide element containing modant, dye and sonic polymer | FUJI PHOTO FILM CO., LTD. (JP) | 1991-05-14 | — | — | US | disclosed |
| EP-0423693-A2 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-04-24 | — | — | EP | disclosed |
| US-4895791-A | ANIONIC POLYMER AND HYDROXY-CONTAINING COMPOUND; STRESS RESISTANCE; WITHSTANDS PRESSURE AND BENDING; MECHANICAL PROPERTIES | FUJI PHOTO FILM CO., LTD. (JP) | 1990-01-23 | — | — | US | disclosed |