Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.48 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.48 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.53 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.53 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28437698 | 0.96 | MEN1 (0.55) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| 4-Nonylphenol SCHEMBL11335761 | 0.94 | NR5A1 (0.58) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL11511436 | 0.94 | MEN1 (0.61) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| Potassium Ion SCHEMBL29760204 | 0.93 | MEN1 (0.55) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL4459952 | 0.88 | MEN1 (0.64) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL27518731 | 0.88 | MEN1 (0.64) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL4579599 | 0.85 | FUT7 (0.43) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL2686941 | 0.84 | S1PR1 (0.67) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL13763215 | 0.83 | ALDH1A1 (0.71) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL9357898 | 0.83 | ALDH1A1 (0.71) | MEN1USP2ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288059-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1994-02-23 | — | — | EP | disclosed |
| US-5153115-A | A backing or subbing antistatic layer comprising an acrylic ester, amide or ketone having ether, amine and/or sulfide groups; high-speed, automatic development protection | FUJI PHOTO FILM CO., LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| US-5028516-A | Method of forming an image comprising rapidly developing an infrared sensitized photographic material comprising surfactants | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0401826-A1 | Silver halide photographic materials and method for manufacture thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4943520-A | SUBBING LAYER OF POLYOLS; ENDCAPPED POLYETHERS | FUJI PHOTO FILM CO., LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4891307-A | ANTISTATIC SURFACTANTS | FUJI PHOTO FILM CO., LTD. (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0288059-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-10-26 | — | — | EP | disclosed |
| US-4358532-A | Photographic element | FUJI PHOTO FILM CO., LTD. (JP) | 1982-11-09 | — | — | US | disclosed |
| US-4336322-A | DYE RELEASING REDOX COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1982-06-22 | — | — | US | disclosed |
| US-4198478-A | AN ANIONIC SURFACTANT POLYMER OF SULFATE OR SULFONATE-MODIFIED ALKYLPHENOL-FORMALDEHYDE RESIN | FUJI PHOTO FILM CO., LTD. (JP) | 1980-04-15 | — | — | US | disclosed |