Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462107 | 0.89 | KCNN4 (0.50) | KCNN4RAB9AMEN1NPC1HTT | |
| SCHEMBL4476738 | 0.89 | CYP19A1 (0.50) | KCNN4RAB9AUSP2CYP19A1MEN1 | |
| SCHEMBL11864838 | 0.87 | SMN1; SMN2 (0.41) | KCNN4RAB9AUSP2CA1CA2 | |
| SCHEMBL11867010 | 0.87 | SMN1; SMN2 (0.50) | KCNN4RAB9AUSP2ACHEMEN1 | |
| SCHEMBL11871260 | 0.82 | KCNN4 (0.51) | KCNN4ACHECYP19A1CYP3A4CYP2D6 | |
| SCHEMBL11861140 | 0.82 | TSHR (0.56) | RAB9ACYP19A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11869841 | 0.82 | ALDH1A1 (0.42) | KCNN4CYP19A1MAPK1 | |
| SCHEMBL11861313 | 0.82 | NFE2L2 (0.53) | RAB9ACA1CA2CA7CA9 | |
| SCHEMBL11868417 | 0.82 | KDM4E (0.48) | CA2CA9CYP19A1 | |
| SCHEMBL3158793 | 0.81 | TSHR (0.50) | KCNN4RAB9AUSP2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292264-A1 | Process for Manufacture of Fluorinated Benzenes and Fluorinated Benzophenones, and Derivatives Thereof | FUJIAN YONGJING TECHNOLOGY CO., LTD (CN) | 2021-09-23 | — | — | US | disclosed |
| US-11008273-B2 | Process for the manufacture of fluorinated benzenes and fluorinated benzophenones, and derivatives thereof | FUJIAN YONGJING TECHNOLOGY CO., LTD (CN) | 2021-05-18 | — | — | US | disclosed |
| WO-2020164291-A1 | NEW PROCESS FOR MANUFACTURE OF FLUORINATED BENZENES AND FLUORINATED BENZOPHENONES, AND DERIVATIVES THEREOF | FUJIAN YONGJING TECHNOLOGY CO., LTD (CN) | 2020-08-20 | — | — | WO | disclosed |
| US-20200262776-A1 | New Process for the Manufacture of Fluorinated Benzenes and Fluorinated Benzophenones, and Derivatives Thereof | FUJIAN YONGJING TECHNOLOGY CO., LTD (CN) | 2020-08-20 | — | — | US | disclosed |
| US-20200262775-A1 | Process for Friedel-Crafts Reaction, and Catalyst Therefore | FUJIAN YONGJING TECHNOLOGY CO., LTD. (CN) | 2020-08-20 | — | — | US | disclosed |
| US-7576088-B2 | Benzodioxole derivatives | HOFFMAN-LA ROCHE INC. (US) | 2009-08-18 | — | — | US | disclosed |
| US-7427688-B2 | Production method of optically active diphenylalanine compounds | AJINOMOTO CO., INC. (JP) | 2008-09-23 | — | — | US | disclosed |
| EP-1532132-B1 | NOVEL BENZODIOXOLES | HOFFMANN LA ROCHE (CH) | 2008-03-19 | — | — | EP | disclosed |
| US-7321055-B2 | Production method of optically active dephenylalanine compounds | AJINOMOTO CO., INC. (JP) | 2008-01-22 | — | — | US | disclosed |
| US-20070032658-A1 | Production method of optically active dephenylalanine compounds | AJINOMOTO CO., INC. (JP) | 2007-02-08 | — | — | US | disclosed |
| EP-1724253-A2 | Production method of optically active diphenylalanine compounds | Ajinomoto Co., Inc. (JP) | 2006-11-22 | — | — | EP | disclosed |
| US-20050143373-A1 | Benzodioxole derivatives | ALANINE ALEXANDER (FR) | 2005-06-30 | — | — | US | disclosed |
| US-6900227-B2 | Benzodioxole derivatives | HOFFMANN-LA ROCHE INC. (US) | 2005-05-31 | — | — | US | disclosed |
| EP-1532132-A1 | NOVEL BENZODIOXOLES | F.HOFFMANN-LA ROCHE AG (CH) | 2005-05-25 | — | — | EP | disclosed |
| US-20040142922-A1 | Benzodioxole derivatives | HOFFMANN-LA ROCHE INC. | 2004-07-22 | — | — | US | disclosed |
| WO-2004013120-A1 | NOVEL BENZODIOXOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-02-12 | — | — | WO | disclosed |
| EP-0096008-B1 | (+)-CYANIDAN-3-OL DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL PREPARATIONS THAT CONTAIN SUCH COMPOUNDS, AND THE USE OF THE LATTER | Zyma SA (CH) | 1989-03-29 | — | — | EP | disclosed |
| US-4510159-A | (+)-Cyanidan-3-ol derivatives, pharmaceutical preparations that contain such compounds, and the use of the latter to treat liver or venous diseases | ZYMA SA (CH) | 1985-04-09 | — | — | US | disclosed |
| EP-0096008-A2 | (+)-Cyanidan-3-ol derivatives, processes for their manufacture, pharmaceutical preparations that contain such compounds, and the use of the latter | Zyma SA (CH) | 1983-12-07 | — | — | EP | disclosed |
| US-3985766-A | ANTIMYCOTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11008273-B2 | Process for the manufacture of fluorinated benzenes and fluorinated benzophenones, and derivatives thereof | PFAS, PFKFB4, PFKFB2 | KCNN4 2364/4885RAB9A 1980/4885USP2 2389/4885 |
| US-20050143373-A1 | Benzodioxole derivatives | CNR2, CNR1, GPR119 | KCNN4 1843/4885RAB9A 2171/4885USP2 2511/4885 |
| US-20200262776-A1 | New Process for the Manufacture of Fluorinated Benzenes and Fluorinated Benzophenones, and Derivatives Thereof | PFAS, PFKFB4, PFKFB1 | KCNN4 2603/4885RAB9A 1869/4885USP2 2219/4885 |
| US-20210292264-A1 | Process for Manufacture of Fluorinated Benzenes and Fluorinated Benzophenones, and Derivatives Thereof | PFAS, PFKFB4, PFKFB2 | KCNN4 2601/4885RAB9A 2013/4885USP2 2416/4885 |
| US-20070032658-A1 | Production method of optically active dephenylalanine compounds | TYR, PAH, DDC | KCNN4 2745/4885RAB9A 1585/4885USP2 3037/4885 |
| US-20200262775-A1 | Process for Friedel-Crafts Reaction, and Catalyst Therefore | HNF4A, TFEB, HACL2 | KCNN4 2997/4885RAB9A 2823/4885USP2 2631/4885 |
| US-20040142922-A1 | Benzodioxole derivatives | CNR1, CNR2, GPR119 | KCNN4 1690/4885RAB9A 2321/4885USP2 2997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.