Sugi Predict

Sugi Predict / Compounds / SCHEMBL4463047

SCHEMBL4463047

SCHEMBL4463047

CC(=O)Nc1ccc(S(=O)(=O)NC(=O)c2ccccc2OC(F)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AVPR2 P30518 1/20 0.52
▸ GPR27 Q9NS67 1/20 0.52
▸ HTT P42858 3/20 0.51
▸ KCNK3 O14649 3/20 0.50
▸ KCNK9 Q9NPC2 3/20 0.50
▸ ALDH1A1 P00352 3/20 0.50
▸ BDKRB1 P46663 3/20 0.48
▸ KDM4E B2RXH2 1/20 0.48
▸ HSD17B10 Q99714 2/20 0.47
▸ LMNA P02545 1/20 0.47
▸ IDO1 P14902 1/20 0.47
▸ CA1 P00915 1/20 0.47
▸ CA2 P00918 1/20 0.47
▸ MMP1 P03956 1/20 0.47
▸ MMP2 P08253 1/20 0.47
▸ MMP9 P14780 1/20 0.47
▸ MMP8 P22894 1/20 0.47
▸ MMP13 P45452 1/20 0.47
▸ POLB P06746 1/20 0.47
▸ MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4477116 0.84 LIPE (0.50) AVPR2GPR27HTTKCNK3KCNK9
SCHEMBL4475149 0.83 LIPE (0.48) AVPR2GPR27ALDH1A1LMNA
SCHEMBL4472735 0.82 ALDH1A1 (0.53) AVPR2GPR27HTTALDH1A1BDKRB1
SCHEMBL14607436 0.80 ALDH1A1 (0.59) HTTALDH1A1BDKRB1KDM4ELMNA
SCHEMBL15449709 0.79 ALDH1A1 (0.76) HTTALDH1A1BDKRB1KDM4EIDO1
SCHEMBL4476646 0.79 FLT1 (0.72) HTTALDH1A1BDKRB1LMNAIDO1
SCHEMBL27503989 0.79 SMN1; SMN2 (0.50) AVPR2GPR27HTTKCNK3KCNK9
SCHEMBL10223119 0.79 HSD17B10 (0.59) ALDH1A1KDM4EHSD17B10LMNAIDO1
SCHEMBL10223118 0.76 NPC1 (0.56) HTTALDH1A1BDKRB1KDM4ELMNA
SCHEMBL15495162 0.75 RXFP1 (0.60) GPR27HTTALDH1A1HSD17B10CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605111-B2 Herbicides SYNGENTA CROP PROTECTION, INC. (US) 2009-10-20 — — US disclosed
US-7459414-B2 Herbicides SYNGENTA CROP PROTECTION, INC. (US) 2008-12-02 — — US disclosed
US-20080200336-A1 HERBICIDAL COMPOSITION SYNEGENTA CROP PROTECTION, INC. (US) 2008-08-21 — — US disclosed
CN-1272324-C Novel herbicides SYNGENTA PARTICIPATIONS AG (CH) 2006-08-30 — — CN disclosed
EP-1481970-B1 Novel herbicides SYNGENTA PARTICIPATIONS AG (CH) 2006-03-22 — — EP disclosed
US-6962894-B1 comprise a herbicide and a safener (counter-agent, antidote) and protect the useful plants, but not the weeds, against the phytotoxic action of the herbicide SYNGENTA CROP PROTECTION, INC. (US) 2005-11-08 — — US disclosed
US-20050187110-A1 mixtures with plant safening agents used for selectively controlling weeds and grasses in crops of useful plants MAETZKE THOMAS (CH) 2005-08-25 — — US disclosed
US-20050164883-A1 agronomically tolerable salts, isomers and enantiomers of those compounds, are suitable for use as herbicides MAETZKE THOMAS (CH) 2005-07-28 — — US disclosed
US-20050164886-A1 Herbicidal compositions ALSONS CORPORATION 2005-07-28 — — US disclosed
US-6894005-B1 Heterocyclic compound containing phenyl groups; postemergence herbicides SYNGENTA CROP PROTECTION, INC. (US) 2005-05-17 — — US disclosed
US-20050090399-A1 Phenyl substituted heterocyclic compounds useful as herbicides FRIEDMANN ADRIAN A (GB) 2005-04-28 — — US disclosed
EP-1481970-A1 Novel herbicides Syngenta Participations AG (CH) 2004-12-01 — — EP disclosed
EP-1210333-B1 p-Tolyl-heterocycles as herbicides SYNGENTA PARTICIPATIONS AG (CH) 2004-11-17 — — EP disclosed
EP-1468000-A1 PHENYL SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS HERBICIDES Syngenta Participations AG (CH) 2004-10-20 — — EP disclosed
CN-1514829-A Novel herbicides �����ɷ� 2004-07-21 — — CN disclosed
WO-2003062244-A1 PHENYL SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2003-07-31 — — WO disclosed
EP-1210333-A2 NOVEL HERBICIDES Syngenta Participations AG (CH) 2002-06-05 — — EP disclosed
EP-1209975-A1 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2002-06-05 — — EP disclosed
WO-2001017972-A2 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 — — WO disclosed
WO-2001017353-A1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050164886-A1 Herbicidal compositions CBR3, CBR1, CNPY2 AVPR2 3553/4885GPR27 1786/4885HTT 4002/4885
US-20050164883-A1 agronomically tolerable salts, isomers and enantiomers of those compounds, are suitable for use as herbicides DDT, SULT2A1, GSTA1 AVPR2 542/4885GPR27 2160/4885HTT 212/4885
US-20080200336-A1 HERBICIDAL COMPOSITION MTX2, DDT, AGPS AVPR2 1936/4885GPR27 1671/4885HTT 873/4885
US-20050090399-A1 Phenyl substituted heterocyclic compounds useful as herbicides DDT, PAH, CYP1A1 AVPR2 1754/4885GPR27 2278/4885HTT 437/4885
US-20050187110-A1 mixtures with plant safening agents used for selectively controlling weeds and grasses in crops of useful plants PIN1, GMDS, DDT AVPR2 860/4885GPR27 4489/4885HTT 981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.