Sugi Predict

Sugi Predict / Compounds / SCHEMBL4477116

SCHEMBL4477116

SCHEMBL4477116

O=C(NS(=O)(=O)c1ccc(NC(=O)C2CC2)cc1)c1ccccc1OC(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LIPE Q05469 1/20 0.50
▸ AVPR2 P30518 1/20 0.48
▸ GPR27 Q9NS67 1/20 0.48
▸ RXFP1 Q9HBX9 1/20 0.46
▸ MAPT P10636 2/20 0.45
▸ HTT P42858 1/20 0.45
▸ LMNA P02545 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ KMT2A Q03164 3/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ KCNK3 O14649 2/20 0.44
▸ KCNK9 Q9NPC2 2/20 0.44
▸ HRH3 Q9Y5N1 1/20 0.43
▸ ENPP3 O14638 2/20 0.43
▸ ENPP1 P22413 2/20 0.43
▸ ENPP2 Q13822 2/20 0.43
▸ ACKR3 P25106 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4475149 0.96 LIPE (0.48) LIPEAVPR2GPR27RXFP1LMNA
SCHEMBL4468235 0.86 MAPT (0.61) RXFP1MAPTHTTKMT2AMEN1
SCHEMBL4463047 0.84 AVPR2 (0.52) AVPR2GPR27MAPTHTTLMNA
SCHEMBL4484204 0.84 RBP4 (0.49) AVPR2GPR27RXFP1MAPTLMNA
SCHEMBL7798059 0.82 MEN1 (0.60) RXFP1MAPTHTTLMNAKMT2A
SCHEMBL4463018 0.82 MEN1 (0.57) RXFP1MAPTHTTLMNAKMT2A
SCHEMBL4485832 0.81 FLT1 (0.65) RXFP1MAPTLMNAL3MBTL1KMT2A
SCHEMBL27555511 0.81 LIPE (0.49) LIPEAVPR2GPR27RXFP1MAPT
SCHEMBL4753755 0.71 KCNK3 (0.72) AVPR2GPR27RXFP1MAPTHTT
SCHEMBL30211340 0.71 KCNK3 (0.72) AVPR2GPR27RXFP1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748343-B2 Herbicide/safener combintions BAYER CROPSCIENCE AG (DE) 2014-06-10 — — US disclosed
US-20120322657-A1 HERBICIDE/SAFENER COMBINTIONS ZIEMER FRANK (DE) 2012-12-20 — — US disclosed
US-7605111-B2 Herbicides SYNGENTA CROP PROTECTION, INC. (US) 2009-10-20 — — US disclosed
US-7459414-B2 Herbicides SYNGENTA CROP PROTECTION, INC. (US) 2008-12-02 — — US disclosed
US-20080200336-A1 HERBICIDAL COMPOSITION SYNEGENTA CROP PROTECTION, INC. (US) 2008-08-21 — — US disclosed
CN-1272324-C Novel herbicides SYNGENTA PARTICIPATIONS AG (CH) 2006-08-30 — — CN disclosed
EP-1481970-B1 Novel herbicides SYNGENTA PARTICIPATIONS AG (CH) 2006-03-22 — — EP disclosed
US-20060030485-A1 Herbicide/safener combinations AVENTIS CROPSCIENCE GMBH 2006-02-09 — — US disclosed
US-6962894-B1 comprise a herbicide and a safener (counter-agent, antidote) and protect the useful plants, but not the weeds, against the phytotoxic action of the herbicide SYNGENTA CROP PROTECTION, INC. (US) 2005-11-08 — — US disclosed
US-20050187110-A1 mixtures with plant safening agents used for selectively controlling weeds and grasses in crops of useful plants MAETZKE THOMAS (CH) 2005-08-25 — — US disclosed
US-20050090399-A1 Phenyl substituted heterocyclic compounds useful as herbicides FRIEDMANN ADRIAN A (GB) 2005-04-28 — — US disclosed
EP-1481970-A1 Novel herbicides Syngenta Participations AG (CH) 2004-12-01 — — EP disclosed
EP-1210333-B1 p-Tolyl-heterocycles as herbicides SYNGENTA PARTICIPATIONS AG (CH) 2004-11-17 — — EP disclosed
EP-1468000-A1 PHENYL SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS HERBICIDES Syngenta Participations AG (CH) 2004-10-20 — — EP disclosed
CN-1514829-A Novel herbicides �����ɷ� 2004-07-21 — — CN disclosed
WO-2003062244-A1 PHENYL SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2003-07-31 — — WO disclosed
EP-1210333-A2 NOVEL HERBICIDES Syngenta Participations AG (CH) 2002-06-05 — — EP disclosed
EP-1209975-A1 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2002-06-05 — — EP disclosed
WO-2001017972-A2 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 — — WO disclosed
WO-2001017353-A1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120322657-A1 HERBICIDE/SAFENER COMBINTIONS DDT, DERL1, SLC16A7 LIPE 2400/4885AVPR2 2564/4885GPR27 929/4885
US-20060030485-A1 Herbicide/safener combinations DDT, DERL1, SLC16A7 LIPE 2251/4885AVPR2 2750/4885GPR27 827/4885
US-20080200336-A1 HERBICIDAL COMPOSITION MTX2, DDT, AGPS LIPE 366/4885AVPR2 1936/4885GPR27 1671/4885
US-20050090399-A1 Phenyl substituted heterocyclic compounds useful as herbicides DDT, PAH, CYP1A1 LIPE 1137/4885AVPR2 1754/4885GPR27 2278/4885
US-20050187110-A1 mixtures with plant safening agents used for selectively controlling weeds and grasses in crops of useful plants PIN1, GMDS, DDT LIPE 1205/4885AVPR2 860/4885GPR27 4489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.