Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 9/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.48 |
| ▸ | HTR3B | O95264 | 3/20 | 0.48 |
| ▸ | HTR3A | P46098 | 3/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL28080108 | 0.86 | USP2 (0.38) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL28106504 | 0.82 | — | — | |
| SCHEMBL261863 | 0.82 | GFER (0.39) | KDM4EALDH1A1TP53THRBHTT | |
| Benzamide SCHEMBL6607765 | 0.81 | OPRD1 (0.50) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL1478216 | 0.80 | NPC1 (0.41) | KDM4EALDH1A1TP53THRBHTT | |
| SCHEMBL3833537 | 0.78 | LMNA (0.48) | KDM4EALDH1A1TP53CYP1A2HTT | |
| SCHEMBL28101765 | 0.77 | ADRA2C (0.41) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL28583221 | 0.76 | CHRNB2 (0.38) | HTR3AHTR6ALDH1A1HTR1AHTR2A | |
| SCHEMBL7189439 | 0.75 | HDAC8 (0.34) | KDM4EDRD2DRD3 | |
| SCHEMBL9933428 | 0.72 | ADRB1 (0.52) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071517-A | Crystal form of brexpiprazole and preparation method thereof | 浙江华海药业股份有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-107936005-A | One kind is according to piperazine azoles novel crystal forms II and preparation method thereof | 上海科胜药物研发有限公司 | 2018-04-20 | — | — | CN | claimed |
| CN-107365305-A | One kind is according to piperazine azoles novel crystal forms and preparation method thereof | 上海奥博生物医药技术有限公司 | 2017-11-21 | — | — | CN | claimed |
| CN-120192314-A | Aryl heterocycle Kv1.3 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-117946111-A | Aryl heterocycle Kv1.3 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-04-30 | — | — | CN | disclosed |
| US-11851391-B2 | Antifungal compounds and methods of forming the same | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2023-12-26 | — | — | US | disclosed |
| US-11564394-B2 | Distorted gold (I)-phosphine complexes and and methods for use as antifungal agents | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2023-01-31 | — | — | US | disclosed |
| US-20210195903-A1 | DISTORTED GOLD (I)-PHOSPHINE COMPLEXES AND AND METHODS FOR USE AS ANTIFUNGAL AGENTS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2021-07-01 | — | — | US | disclosed |
| US-20200024224-A1 | ANTIFUNGAL COMPOUNDS AND METHODS OF FORMING THE SAME | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2020-01-23 | — | — | US | disclosed |
| CN-110461842-A | FUSED PENTACYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB BIOPHARMA SPRL | 2019-11-15 | — | — | CN | disclosed |
| CN-109988162-A | One kind is according to piperazine Zole derivatives and preparation method thereof | 武汉兴华智慧医药科技有限公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-101074242-A | Cells accumulation for sphosphonate analogs of HIV protease inhibitor compound and the same compound | GILEAD SCIENCES INC (US) | 2007-11-21 | — | — | CN | disclosed |
| US-20060142365-A1 | Benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2006-06-29 | — | — | US | disclosed |
| US-7030150-B2 | Benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2006-04-18 | — | — | US | disclosed |
| US-20040166137-A1 | Hetero-substituted benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2004-08-26 | — | — | US | disclosed |
| US-20030119754-A1 | Benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2003-06-26 | — | — | US | disclosed |
| EP-0889881-B1 | NEW TRIAZOLES AS THERAPEUTIC AGENTS FOR FUNGAL INFECTIONS | NAEJA PHARMACEUTICAL INC (CA) | 2003-04-23 | — | — | EP | disclosed |
| US-6153616-A | Triazoles as therapeutic agents for fungal infections | SYNPHAR LABORATORIES, INC. (CA) | 2000-11-28 | — | — | US | disclosed |
| EP-0889881-A1 | NEW TRIAZOLES AS THERAPEUTIC AGENTS FOR FUNGAL INFECTIONS | SYNPHAR LABORATORIES INC. (CA) | 1999-01-13 | — | — | EP | disclosed |
| WO-1998031675-A1 | NEW TRIAZOLES AS THERAPEUTIC AGENTS FOR FUNGAL INFECTIONS | SYNPHAR LABORATORIES, INC. (US) | 1998-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11564394-B2 | Distorted gold (I)-phosphine complexes and and methods for use as antifungal agents | DPM1, DSTN, PHOSPHO1 | ADRB1 4833/4885HTR3E 4526/4885HTR3B 4115/4885 |
| US-20210195903-A1 | DISTORTED GOLD (I)-PHOSPHINE COMPLEXES AND AND METHODS FOR USE AS ANTIFUNGAL AGENTS | DPM1, DSTN, PHOSPHO1 | ADRB1 4833/4885HTR3E 4526/4885HTR3B 4115/4885 |
| US-20060142365-A1 | Benzimidazole compounds and antiviral uses thereof | MAVS, ZC3HAV1, TIMM13 | ADRB1 3415/4885HTR3E 1875/4885HTR3B 3144/4885 |
| US-11851391-B2 | Antifungal compounds and methods of forming the same | DPM1, ERG28, SUCLG1 | ADRB1 4317/4885HTR3E 4700/4885HTR3B 4264/4885 |
| US-20200024224-A1 | ANTIFUNGAL COMPOUNDS AND METHODS OF FORMING THE SAME | DPM1, ERG28, SUCLG1 | ADRB1 4317/4885HTR3E 4700/4885HTR3B 4264/4885 |
| US-20030119754-A1 | Benzimidazole compounds and antiviral uses thereof | MAVS, ZC3HAV1, TIMM13 | ADRB1 3415/4885HTR3E 1875/4885HTR3B 3144/4885 |
| US-20040166137-A1 | Hetero-substituted benzimidazole compounds and antiviral uses thereof | MAVS, TIMM13, TIMM10 | ADRB1 2875/4885HTR3E 368/4885HTR3B 824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.