Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4822863 | 0.84 | MAOB (0.39) | MAOBMAOACDC25BCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL3597821 | 0.82 | MAOB (0.38) | MAOBMAOACDC25BCYP11B1CYP11B2 | |
| SCHEMBL13708804 | 0.81 | MAOB (0.46) | MAOBMAOACDC25BCYP11B1CYP11B2 | |
| SCHEMBL11557933 | 0.73 | KMT2A (0.49) | MAOBMAOAMAPTAAK1MEN1 | |
| SCHEMBL11660603 | 0.72 | MAOB (0.55) | MAOBMAOASMN1; SMN2MAPTATM | |
| SCHEMBL31618253 | 0.71 | MAOA (0.38) | MAOBMAOACDC25BCYP11B1CYP11B2 | |
| SCHEMBL13708805 | 0.70 | MAOB (0.71) | MAOBSMN1; SMN2MAPTATMMEN1 | |
| 3-Coumaranone SCHEMBL29420742 | 0.70 | PKM (0.56) | MAOBMAOASMN1; SMN2MAPTATM | |
| 3-Coumaranone SCHEMBL69412 | 0.70 | PKM (0.56) | MAOBMAOASMN1; SMN2MAPTATM | |
| SCHEMBL9923730 | 0.69 | KMT2A (0.32) | MAOBKMT2AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006119820-A1 | AGENTS FOR DYEING KERATIN-BASED FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-11-16 | — | — | WO | claimed |
| US-20230348441-A1 | BICYCLIC COMPOUND THAT ACTS AS CRBN PROTEIN REGULATOR | MEDSHINE DISCOVERY INC. (CN) | 2023-11-02 | — | — | US | disclosed |
| US-8957219-B2 | Acetic acid amide derivative having inhibitory activity on endothelial lipase | SHIONOGI & CO., LTD. (JP) | 2015-02-17 | — | — | US | disclosed |
| US-20140288302-A1 | ACETIC ACID AMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY ON ENDOTHELIAL LIPASE | SHIONOGI & CO., LTD. (JP) | 2014-09-25 | — | — | US | disclosed |
| US-20110251386-A1 | ACETIC ACID AMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY ON ENDOTHELIAL LIPASE | SHIONOGI & CO., LTD. (JP) | 2011-10-13 | — | — | US | disclosed |
| US-7544693-B2 | Spirofuropyridine aryl derivatives | ASTRAZENECA AB (SE) | 2009-06-09 | — | — | US | disclosed |
| US-20070072887-A1 | Spirofuropyridine aryl derivatives | ASTRAZENECA AB (SE) | 2007-03-29 | — | — | US | disclosed |
| EP-1678183-A1 | SPIROFUROPYRIDINE ARYL DERIVATIVES | AstraZeneca AB (SE) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042538-A1 | SPIROFUROPYRIDINE ARYL DERIVATIVES | ASTRAZENECA AB (SE) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348441-A1 | BICYCLIC COMPOUND THAT ACTS AS CRBN PROTEIN REGULATOR | CRBN, CRKL, NCOR1 | MAOB 4108/4885MAOA 4359/4885CDC25B 3313/4885 |
| US-20070072887-A1 | Spirofuropyridine aryl derivatives | REN, ADRA1D, ADRB1 | MAOB 181/4885MAOA 420/4885CDC25B 3059/4885 |
| US-20110251386-A1 | ACETIC ACID AMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY ON ENDOTHELIAL LIPASE | LIPG, CEL, LIPA | MAOB 568/4885MAOA 458/4885CDC25B 4223/4885 |
| US-20140288302-A1 | ACETIC ACID AMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY ON ENDOTHELIAL LIPASE | LIPG, CEL, FFAR3 | MAOB 536/4885MAOA 473/4885CDC25B 4433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.