Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4524446 | 0.87 | GPR119 (0.40) | GPR119KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL4356808 | 0.86 | SETD7 (0.45) | GPR119KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL4360439 | 0.84 | TSHR (0.44) | GPR119KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL4534565 | 0.82 | KDM4E (0.40) | GPR119KMT2AHPGDALDH1A1GAA | |
| SCHEMBL4531625 | 0.81 | ALDH1A1 (0.40) | ALDH1A1GAAKDM4ENPSR1 | |
| SCHEMBL4349657 | 0.81 | GPR119 (0.44) | GPR119ALDH1A1GAAKDM4ENPSR1 | |
| SCHEMBL4358687 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1KDM4E | |
| SCHEMBL4356877 | 0.80 | ALDH1A1 (0.45) | HPGDALDH1A1KDM4ENPSR1 | |
| SCHEMBL4356470 | 0.79 | GPR119 (0.38) | GPR119KMT2AMEN1CYP2C19ABL1 | |
| SCHEMBL4354023 | 0.79 | SMN1; SMN2 (0.44) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |