Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706206 | 0.81 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL5969166 | 0.79 | FNTA (0.40) | FNTAFNTB | |
| SCHEMBL18692048 | 0.76 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL8717347 | 0.76 | FNTA (0.56) | FNTAFNTB | |
| Potassium Ion SCHEMBL16010671 | 0.75 | PTGS1 (0.30) | — | |
| SCHEMBL620882 | 0.75 | APP (0.38) | — | |
| SCHEMBL5969147 | 0.74 | FNTA (0.46) | FNTAFNTB | |
| Potassium Ion SCHEMBL16009574 | 0.74 | — | — | |
| SCHEMBL219270 | 0.73 | APP (0.37) | — | |
| Potassium Ion SCHEMBL442400 | 0.72 | APP (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230137331-A1 | Activation and Expansion of T Cell Subsets Using Biocompatible Solid Substrates with Tunable Rigidity | UNIV PENNSYLVANIA (US) | 2023-05-04 | — | — | US | claimed |
| US-20150030619-A1 | Activation and Expansion of T Cell Subsets Using Biocompatible Solid Substrates with Tunable Rigidity | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-01-29 | — | — | US | claimed |
| WO-2013036585-A1 | ACTIVATION AND EXPANSION OF T CELL SUBSETS USING BIOCOMPATIBLE SOLID SUBSTRATES WITH TUNABLE RIGIDITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-03-14 | — | — | WO | claimed |
| EP-0930844-B8 | IMPROVED METHODS FOR DIAGNOSTIC IMAGING BY REGULATING THE ADMINISTRATION RATE OF A CONTRAST AGENT | LANTHEUS MEDICAL IMAGING INC (US) | 2008-11-26 | — | — | EP | claimed |
| EP-0930844-B1 | IMPROVED METHODS FOR DIAGNOSTIC IMAGING BY REGULATING THE ADMINISTRATION RATE OF A CONTRAST AGENT | IMARX PHARMACEUTICAL CORP (US) | 2008-09-03 | — | — | EP | claimed |
| JP-4139440-B2 | — | — | 2008-08-27 | — | — | JP | claimed |
| EP-0580726-B2 | LOW DENSITY MICROSPHERES AND THEIR USE AS CONTRAST AGENTS FOR COMPUTED TOMOGRAPHY | IMARX PHARMACEUTICAL CORP (US) | 2008-08-20 | — | — | EP | claimed |
| EP-1017425-B1 | IMPROVED METHODS FOR DIAGNOSTIC IMAGING INVOLVING THE USE OF A CONTRAST AGENT AND A CORONARY VASODILATOR | IMARX PHARMACEUTICAL CORP (US) | 2007-10-17 | — | — | EP | claimed |
| EP-1323434-B1 | Method for diagnostic imaging of the renal region using a contrast agent and a vasodilator | IMARX PHARMACEUTICAL CORP (US) | 2007-07-11 | — | — | EP | claimed |
| US-6998107-B2 | Composition comprising low density microspheres | BRISTOL-MYERS SQUIBB PHARMA COMAPANY (US) | 2006-02-14 | — | — | US | claimed |
| EP-0804932-A2 | Contrast media for diagnostic imaging comprising gas filled microspeures | ImaRx Pharmaceutical Corp. (US) | 1997-11-05 | — | — | EP | claimed |
| WO-1996040285-A1 | NOVEL TARGETED COMPOSITIONS FOR DIAGNOSTIC AND THERAPEUTIC USE | IMARX PHARMACEUTICAL CORP. (US) | 1996-12-19 | — | — | WO | claimed |
| US-5547656-A | Low density microspheres and their use as contrast agents for computed tomography, and in other applications | IMARX PHARMACEUTICAL CORP. (US) | 1996-08-20 | — | — | US | claimed |
| US-5527521-A | AQUEOUS SUSPENSION OF BIOCOMPATIBLE POLYMER, A PERFLUOROCARBON GAS, AND A THICKENING OR SUSPENDING AGENT | IMARX PHARMACEUTICAL CORP. (US) | 1996-06-18 | — | — | US | claimed |
| US-5456900-A | Low density microspheres and their use as contrast agents for computed tomography | CITIZENS BANK, N.A. | 1995-10-10 | — | — | US | claimed |
| EP-0580726-A4 | LOW DENSITY MICROSPHERES AND THEIR USE AS CONTRAST AGENTS FOR COMPUTED TOMOGRAPHY. | UNGER EVAN C (US) | 1995-03-29 | — | — | EP | claimed |
| EP-0580726-A1 | LOW DENSITY MICROSPHERES AND THEIR USE AS CONTRAST AGENTS FOR COMPUTED TOMOGRAPHY | IMARX PHARMACEUTICAL CORP. (US) | 1994-02-02 | — | — | EP | claimed |
| US-5281408-A | Low density microspheres and their use as contrast agents for computed tomography | CITIZENS BANK, N.A. | 1994-01-25 | — | — | US | claimed |
| US-5205290-A | LOW DENSITY MICROSPHERES AND THEIR USE AS CONTRAST AGENTS FOR COMPUTED TOMOGRAPHY | CITIZENS BANK, N.A. | 1993-04-27 | — | — | US | claimed |
| WO-1992017514-A1 | LOW DENSITY MICROSPHERES AND THEIR USE AS CONTRAST AGENTS FOR COMPUTED TOMOGRAPHY | UNGER EVAN C (US) | 1992-10-15 | — | — | WO | claimed |