SCHEMBL453182

SCHEMBL453182

CC(C)(C)c1ccc(S(OS(=O)(=O)c2ccc3ccc4cccc5ccc2c3c45)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 1/20 0.39
HSD11B1 P28845 3/20 0.38
HSD17B3 P37058 1/20 0.38
NLRP3 Q96P20 1/20 0.37
ENPP1 P22413 1/20 0.36
ALDH1A1 P00352 4/20 0.35
NPC1 O15118 1/20 0.35
RECQL P46063 1/20 0.35
RAB9A P51151 1/20 0.35
GLO1 Q04760 1/20 0.34
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
PRSS1 P07477 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
APAF1 O14727 1/20 0.33
NSD2 O96028 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL450357 0.90 ALDH1A1 (0.38) ALDH1A1RECQLPRSS1POLBKDM4E
SCHEMBL3205028 0.88 ALDH1A1 (0.40) ALDH1A1KEAP1NFE2L2KDM4EMEN1
SCHEMBL3204718 0.86 F2 (0.33) ALDH1A1PRSS1KDM4EMEN1MAPT
SCHEMBL3195413 0.85 LMNA (0.45) ALDH1A1KEAP1NFE2L2PRSS1KDM4E
SCHEMBL3199458 0.84 ALDH1A1 (0.36) ALDH1A1HSP90AA1HSP90AB1CA2APAF1
SCHEMBL449950 0.81 LMNA (0.45) ALDH1A1GLO1KEAP1NFE2L2PRSS1
SCHEMBL15675804 0.81 ENPP2 (0.35) ALDH1A1NPC1RAB9APRSS1CA1
SCHEMBL6746249 0.79 HSD11B1 (0.53) HSD11B1HSD17B3NLRP3ENPP1ALDH1A1
SCHEMBL451539 0.78 HSD11B1 (0.53) HSD17B2HSD11B1HSD17B3ENPP1ALDH1A1
SCHEMBL2634260 0.78 HSD11B1 (0.53) HSD17B2HSD11B1HSD17B3ENPP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070031758-A1 Positive-type radiation-sensitive resin composition for producing a metal-plating formed material, transcription film and production method of a metal-plating formed material JSR CORPORATION (JP) 2007-02-08 US claimed
EP-1750176-A2 Positive-type radiation-sensitive resin composition for producing a metal-plating formed material, transcription film and production method of a metal-plating formed material JSR Corporation (JP) 2007-02-07 EP claimed
EP-3010943-B1 CURABLE COMPOSITION, FILM, AND METHOD OF PRODUCING FILM CANON KK (JP) 2024-04-03 EP disclosed
US-11332597-B2 Photo-curable composition and patterning method using the same CANON KABUSHIKI KAISHA (JP) 2022-05-17 US disclosed
EP-2841255-B1 RESIN PRODUCTION METHOD AND RESIN PRODUCTION APPARATUS CANON KK (JP) 2020-05-13 EP disclosed
US-20200123343-A1 PHOTO-CURABLE COMPOSITION AND PATTERNING METHOD USING THE SAME CANON KK (JP) 2020-04-23 US disclosed
US-10472445-B2 Photocurable composition and method for manufacturing film CANON KABUSHIKI KAISHA (JP) 2019-11-12 US disclosed
US-10421853-B2 Photosensitive gas generating agent and photocurable composition CANON KABUSHIKI KAISHA (JP) 2019-09-24 US disclosed
EP-2907156-B1 IMPRINTING METHOD AND CURABLE COMPOSITION FOR IMPRINTING CANON KK (JP) 2019-04-10 EP disclosed
EP-2758987-B1 METHOD OF FORMING A FILM CANON KK (JP) 2019-03-20 EP disclosed
US-10233274-B2 Curable composition and patterning method using the same CANON KABUSHIKI KAISHA (JP) 2019-03-19 US disclosed
EP-1750176-A2 Positive-type radiation-sensitive resin composition for producing a metal-plating formed material, transcription film and production method of a metal-plating formed material JSR Corporation (JP) 2007-02-07 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20060078821-A1 A caroboxyalkylanthracene based compound, a hydroxy or alkoxystyrene polymer, and a sulfonimide compound as photoacid generator; low sublimation properties and excellent compatibility with other components; exhibits optimum controllability of radiation transmittance; microfabrication JSR CORPORATION (JP) 2006-04-13 US disclosed
EP-1640804-A2 Positive-tone radiation-sensitive resin composition JSR Corporation (JP) 2006-03-29 EP disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed
US-20050095527-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-05 US disclosed
US-20030157423-A1 Copolymer, polymer mixture, and radiation-sensitive resin composition JSR CORPORATION (JP) 2003-08-21 US disclosed
US-20020090569-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10421853-B2 Photosensitive gas generating agent and photocurable composition PFN1, PFAS, FRG1 HSD17B2 3992/4885HSD11B1 4332/4885HSD17B3 4273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.