Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13586012 | 0.85 | HDAC1 (0.47) | LMNAHTTMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13586274 | 0.82 | CTSC (0.36) | LMNAMAPK1TSHRACKR3 | |
| SCHEMBL4351462 | 0.81 | HTR1A (0.40) | LMNAMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL4355465 | 0.80 | HTR1A (0.35) | LMNAMAPK1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4353770 | 0.80 | NPY2R (0.42) | ALDH1A1HSD17B10 | |
| SCHEMBL4538463 | 0.80 | NPY2R (0.39) | LMNAMAPK1ALDH1A1HSD17B10TSHR | |
| SCHEMBL13586016 | 0.79 | SMN1; SMN2 (0.43) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL13586042 | 0.79 | CYP3A4 (0.38) | LMNAHTTMAPTMAPK1ALDH1A1 | |
| SCHEMBL4541603 | 0.78 | GPR142 (0.48) | NPSR1MEN1KMT2ASYKCNR1 | |
| SCHEMBL4351631 | 0.77 | ALDH1A1 (0.40) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |